OBO-Protected Pyruvates as Reagents for the Synthesis of Functionalized Heteroaromatic Compounds.
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DOI: 10.1021/acs.orglett.8b01614
Abstract: Pd-catalyzed α-arylation of methyl-OBO-ketone (OBO = 4-methyl-2,6,7-trioxabicyclo[2.2.2]octan-1-yl) gives rise to arylated OBO-protected pyruvates. By appropriate prefunctionalization of the aryl ring or by subsequent functionalization at the α-carbonyl position of the arylated OBO-ketones, useful diketo OBO-protected… read more here.
Keywords: pyruvates reagents; synthesis functionalized; heteroaromatic compounds; protected pyruvates ... See more keywords