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   Articles with "real world" as a keyword



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Comparing Cardiovascular Outcomes With Degarelix or Leuprolide as Prostate Cancer Therapy-Applying Real-world Data to Clinical Trial Emulation.

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recommendations! Published in 2021 at "JAMA network open"

DOI: 10.1001/jamanetworkopen.2021.31429

Abstract: Since the early 1980s, androgen deprivation therapy (ADT) with gonadotropin-releasing hormone (GnRH) agonist or antagonist therapies has remained the primary systemic therapy for men with prostate cancer, owing to the fundamental reliance of the disease… read more here.

Keywords: real world; trial; comparing cardiovascular; prostate cancer ... See more keywords

Real-world Associations of US Cystic Fibrosis Newborn Screening Programs With Nutritional and Pulmonary Outcomes.

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recommendations! Published in 2022 at "JAMA pediatrics"

DOI: 10.1001/jamapediatrics.2022.2674

Abstract: Importance Newborn screening (NBS) for cystic fibrosis (CF) has been universal in the US since 2010, but its association with clinical outcomes is unclear. Objective To describe the real-world effectiveness of NBS programs for CF… read more here.

Keywords: age; cohort; age years; newborn screening ... See more keywords

Real‐world experience with eculizumab and switching to ravulizumab for generalized myasthenia gravis

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recommendations! Published in 2024 at "Annals of Clinical and Translational Neurology"

DOI: 10.1002/acn3.52051

Abstract: Eculizumab and ravulizumab are complement protein C5 inhibitors, showing efficacy and tolerability for patients with anti‐acetylcholine receptor‐positive (AChR+) generalized myasthenia gravis (gMG) in phase 3 clinical trials and subsequent analyses. The purpose of the present… read more here.

Keywords: eculizumab switching; generalized myasthenia; switching ravulizumab; real world ... See more keywords

SEEG‐RFTC in patients with refractory focal epilepsy: real‐world outcomes from 121 cases

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recommendations! Published in 2024 at "Annals of Clinical and Translational Neurology"

DOI: 10.1002/acn3.52117

Abstract: Radiofrequency thermocoagulation (RFTC) has emerged as an effective and safe treatment method for patients with refractory focal epilepsy, when stereo‐electroencephalography (SEEG) is implanted. Although real‐world research results are still limited, a considerable number of patients… read more here.

Keywords: seeg rftc; patients refractory; real world; focal epilepsy ... See more keywords

Real‐world clinical experience with serum MOG and AQP4 antibody testing by live versus fixed cell‐based assay

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recommendations! Published in 2025 at "Annals of Clinical and Translational Neurology"

DOI: 10.1002/acn3.52310

Abstract: To assess the real‐world performance of a live (LCBA) versus a fixed (FCBA) cell‐based assay for the detection of serum antibodies directed against myelin oligodendrocyte glycoprotein (MOG‐IgG) and aquaporin‐4 (AQP4‐IgG). read more here.

Keywords: real world; versus fixed; cell based; based assay ... See more keywords

Basiliximab for steroid‐refractory acute graft‐versus‐host disease: A real‐world analysis

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recommendations! Published in 2022 at "American Journal of Hematology"

DOI: 10.1002/ajh.26475

Abstract: Steroid‐refractory (SR) acute graft‐versus‐host disease (aGVHD) is one of the leading causes of early mortality after allogeneic hematopoietic stem cell transplantation (allo‐HSCT). We investigated the efficacy, safety, prognostic factors, and optimal therapeutic protocol for SR‐aGVHD… read more here.

Keywords: basiliximab; steroid refractory; refractory acute; acute graft ... See more keywords

Real‐world Big‐data: Strengths and weaknesses of ASCO's CancerLinQ® discovery multiple myeloma dataset

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recommendations! Published in 2023 at "American Journal of Hematology"

DOI: 10.1002/ajh.26921

Abstract: Real-world data (RWD) are increasingly relevant in oncology practice. RWD can shed light on outcomes of patients who are underrepresented or ineligible for clinical trials or with rare cancers that are difficult to study prospectively.… read more here.

Keywords: oncology; cancerlinq discovery; rwd; multiple myeloma ... See more keywords
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Real‐World Effectiveness of Initial Disease‐Modifying Therapies in Pediatric Multiple Sclerosis

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recommendations! Published in 2020 at "Annals of Neurology"

DOI: 10.1002/ana.25737

Abstract: To assess real‐world effectiveness of initial treatment with newer compared to injectable disease‐modifying therapies (DMTs) on disease activity in pediatric multiple sclerosis (MS) and clinically isolated syndrome (CIS). read more here.

Keywords: real world; effectiveness initial; world effectiveness; modifying therapies ... See more keywords

Real-World Outcomes of Endovascular Thrombectomy for Basilar Artery Occlusion: Results of the BArONIS Study.

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recommendations! Published in 2023 at "Annals of neurology"

DOI: 10.1002/ana.26640

Abstract: OBJECTIVE To evaluate clinical outcomes of endovascular thrombectomy (EVT) for acute basilar artery occlusion (BAO) using population-level data from the United States. METHODS Weighted discharge data from the National Inpatient Sample were queried to identify… read more here.

Keywords: outcomes endovascular; endovascular thrombectomy; basilar artery; artery occlusion ... See more keywords

Effectiveness and safety of long‐term therapy with alirocumab in acute coronary syndrome patients: A single‐centre retrospective real‐world study

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recommendations! Published in 2025 at "British Journal of Clinical Pharmacology"

DOI: 10.1002/bcp.70072

Abstract: Although guidelines recommend in‐hospital initiation of high‐intensity statin therapy in patients with acute coronary syndromes (ACS), low‐density lipoprotein cholesterol (LDL‐C) target levels are frequently not attained. Alirocumab has been demonstrated to be a fast‐acting and… read more here.

Keywords: therapy; acute coronary; real world; world ... See more keywords

Exploring Definity-related adverse reaction: A real-world pharmacovigilance study via FAERS database analysis.

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recommendations! Published in 2025 at "British journal of clinical pharmacology"

DOI: 10.1002/bcp.70295

Abstract: AIMS Definity, an ultrasound contrast agent (UCA), is widely utilized in echocardiography. Real-world studies on the safety of Definity in large populations are still lacking. This study aims to explore Definity-related adverse events via real-world… read more here.

Keywords: analysis; real world; definity; definity related ... See more keywords