ASH2L-Promoted HOXC8 Gene Expression Plays a Role in Mixed Lineage Leukemia-Rearranged Acute Leukemia
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DOI: 10.2147/ott.s221643
Abstract: Background Mixed lineage leukemia (MLL) fusion protein alone exhibits poor histone lysine methyltransferase (HKMT) activity in catalyzing histone H3 Lys4 trimethylation (H3K4me3) in MLL-rearranged acute leukemia. Methods To explore the HKMT effect of another regulatory… read more here.
Keywords: leukemia; rearranged acute; expression; acute leukemia ... See more keywords
Co-occurrence of CRLF2-rearranged and Ph+ acute lymphoblastic leukemia: a report of four patients
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DOI: 10.3324/haematol.2016.161000
Abstract: Ph-like acute lymphoblastic leukemia (Ph-like ALL) represents a high-risk subgroup of B-cell ALL.[1][1]–[7][2] By gene-expression, these patients have a profile similar to that of Ph+ ALL; however, they lack the BCR-ABL1 fusion. Patients with Ph-like… read more here.
Keywords: lymphoblastic leukemia; rearranged acute; crlf2 rearranged; acute lymphoblastic ... See more keywords