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   Articles with "rearranged acute" as a keyword



KRAS mutation status critically determines the clinical outcome of patients with KMT2A‐rearranged acute myeloid leukemia

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recommendations! Published in 2025 at "Cancer"

DOI: 10.1002/cncr.35941

Abstract: KMT2A(11q23)‐rearranged acute myeloid leukemia (KMT2A‐r AML) represents a clinically aggressive subtype with heterogeneous outcomes. Current evidence remains inconclusive regarding the prognostic relevance of fusion partners in 11q23/KMT2A‐rearranged AML. The comprehensive mutational landscape and prognostic implications… read more here.

Keywords: acute myeloid; kmt2a rearranged; myeloid leukemia; rearranged acute ... See more keywords

Clinical study of single-center PDT-ALL-2016 regimen in the treatment of KMT2A-rearranged acute lymphoblastic leukemia

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recommendations! Published in 2025 at "Blood"

DOI: 10.1182/blood-2025-6866

Abstract: Objective:To investigate the efficacy and prognostic factors of single-center PDT-ALL-2016 regimen in the treatment of patients with KMT2A-rearranged acute lymphoblastic leukemia(KMT2A-r ALL). Methods：A total of 57 diagnosed patients with KMT2A-r ALL who received treatment in… read more here.

Keywords: pdt 2016; year; treatment; 2016 regimen ... See more keywords

ASH2L-Promoted HOXC8 Gene Expression Plays a Role in Mixed Lineage Leukemia-Rearranged Acute Leukemia

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recommendations! Published in 2020 at "OncoTargets and therapy"

DOI: 10.2147/ott.s221643

Abstract: Background Mixed lineage leukemia (MLL) fusion protein alone exhibits poor histone lysine methyltransferase (HKMT) activity in catalyzing histone H3 Lys4 trimethylation (H3K4me3) in MLL-rearranged acute leukemia. Methods To explore the HKMT effect of another regulatory… read more here.

Keywords: leukemia; rearranged acute; expression; acute leukemia ... See more keywords
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Co-occurrence of CRLF2-rearranged and Ph+ acute lymphoblastic leukemia: a report of four patients

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recommendations! Published in 2017 at "Haematologica"

DOI: 10.3324/haematol.2016.161000

Abstract: Ph-like acute lymphoblastic leukemia (Ph-like ALL) represents a high-risk subgroup of B-cell ALL.[1][1]–[7][2] By gene-expression, these patients have a profile similar to that of Ph+ ALL; however, they lack the BCR-ABL1 fusion. Patients with Ph-like… read more here.

Keywords: lymphoblastic leukemia; rearranged acute; crlf2 rearranged; acute lymphoblastic ... See more keywords