A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction
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DOI: 10.1038/s41388-018-0666-5
Abstract: Survival rates for pediatric patients suffering from mixed lineage leukemia (MLL)-rearranged leukemia remain below 50% and more targeted, less toxic therapies are urgently needed. A screening method optimized to discover cytotoxic compounds selective for MLL-rearranged… read more here.
Keywords: mll rearranged; subset mll; leukemia cells; rearranged leukemia ... See more keywords