Rearrangement Reactions leading to Optically Active α,α‐Disubstituted Primary Allylamines
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.201601446
Abstract: Synthetic routes to α,α-disubstituted allylamines have been examined. Racemic compounds were conveniently prepared by thermal Overman rearrangements of primary allyl alcohols with trisubstituted double bonds, but rearrangement of these substrates by the only commercially available… read more here.
Keywords: optically active; reactions leading; rearrangement reactions; active disubstituted ... See more keywords
Rearrangement in Stereoretentive Syntheses of Menthyl Chloride from Menthol: Insight into Competing Reaction Pathways through Component Quantification Analysis
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.201700677
Abstract: The enantiopure reagent menthyl chloride (2) is generally prepared from (-)-(1R)-menthol (1) with Lucas' reagent (ZnCl2 in conc. aqueous HCl) in a stereoretentive reaction that appeared to be free from accompanying rearrangements. The same was… read more here.
Keywords: rearrangement stereoretentive; stereoretentive syntheses; reaction; rearrangement ... See more keywords
The Retro‐Claisen Rearrangement of 2‐Vinylcyclopropylcarbonyl Substrates and the Question of its Synthetic Potential
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.202000136
Abstract: The retro-Claisen [3,3]-sigmatropic rearrangement of ,-enoyl compounds allows to form a CO bond while breaking a CC bond in a concerted process. It is rarely observed with acyclic substrates. However, when the alkene and carbonyl… read more here.
Keywords: rearrangement; retro claisen; claisen rearrangement; rearrangement vinylcyclopropylcarbonyl ... See more keywords
A novel HNRNPH1::ERG rearrangement in aggressive acute myeloid leukemia
Sign Up to like & getrecommendations! Published in 2022 at "Genes"
DOI: 10.1002/gcc.23051
Abstract: FUS::ERG rearrangement is a recurrent abnormality seen in a subgroup of acute myeloid leukemia (AML) with a poor prognosis. We described here a novel HNRNPH1::ERG rearrangement in a de novo AML. The patient was unresponsive… read more here.
Keywords: erg rearrangement; aml; fus erg; hnrnph1 erg ... See more keywords
Symmetric finite representability of $$\ell ^p$$-spaces in rearrangement invariant spaces on $$(0,\infty )$$
Sign Up to like & getrecommendations! Published in 2021 at "Mathematische Annalen"
DOI: 10.1007/s00208-021-02277-5
Abstract: Abstract. For a separable rearrangement invariant space X on (0,∞) of fundamental type we identify the set of all p ∈ [1,∞] such that l is finitely represented in X in such a way that… read more here.
Keywords: representability ell; finite representability; rearrangement invariant; ell spaces ... See more keywords
EWSR1 rearrangement is a frequent event in papillary thyroid carcinoma and in carcinoma of the thyroid with Ewing family tumor elements (CEFTE)
Sign Up to like & getrecommendations! Published in 2017 at "Virchows Archiv"
DOI: 10.1007/s00428-017-2095-1
Abstract: Carcinomas of the thyroid with Ewing family tumor element (CEFTEs) are small-cell thyroid tumors with epithelial differentiation that disclose p63 expression and EWSR1-FLI1 rearrangement, carry a favorable prognosis and may co-exist with papillary thyroid carcinoma… read more here.
Keywords: ptc; carcinoma; ewsr1 rearrangement; rearrangement ... See more keywords
Prognostic value and characterization of NTRK1 variation by fluorescence in situ hybridization in esophageal squamous cell carcinoma
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cancer Research and Clinical Oncology"
DOI: 10.1007/s00432-021-03578-7
Abstract: Rearrangement of the neurotrophic tyrosine kinase receptor (NTRK) 1 gene is a target of tropomyosin receptor kinase A (TRKA) inhibitors, and its targeted drug (larotrectinib) has been approved by the US Food and Drug Administration.… read more here.
Keywords: variation; cell carcinoma; squamous cell; rearrangement ... See more keywords
Multi-Step Rearrangement Mechanism for Acetyl Cedrene to the Hydrocarbon Follower†
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DOI: 10.1007/s10600-017-2085-1
Abstract: Conversion of acetyl cedrene (2) to its follower (3) using acetic anhydride and polyphosphoric acid involves a multi-step cationic molecular rearrangement, which is consistent with deuteriation and 1-13C labeling studies of acetyl cedrene. The key… read more here.
Keywords: acetyl cedrene; step; rearrangement; follower ... See more keywords
2,6-Disubstituted 4-azidopyrimidines: synthesis, kinetic and thermodynamic studies of azide-tetrazole rearrangement by NMR spectroscopy
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DOI: 10.1007/s11172-017-1986-2
Abstract: Thermodynamic and kinetic parameters of the tautomeric tetrazole-azide rearrangement for a series of 2,6-disubstituted 4-azidopyrimidines are determined by NOESY/EXSY and DNMR: ΔH = 15—28 kJ mol–1; ΔS = 47—65 J mol–1 К–1; Еa = 93—117… read more here.
Keywords: disubstituted azidopyrimidines; kinetic thermodynamic; spectroscopy; rearrangement ... See more keywords
Plakoglobin is involved in cytoskeletal rearrangement of podocytes under the regulation of UCH-L1.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.05.093
Abstract: UCH-L1 is a de-ubiquitination enzyme comprehensively distributed in neural cells and podocytes, which is involved in several kinds of nervous system and kidney related diseases. Our previous studies have demonstrated the aberrant up-regulation of UCH-L1… read more here.
Keywords: regulation uch; rearrangement podocytes; rearrangement; plakoglobin involved ... See more keywords
Molecular approaches identify a cryptic MECOM rearrangement in a child with a rapidly progressive myeloid neoplasm.
Sign Up to like & getrecommendations! Published in 2018 at "Cancer genetics"
DOI: 10.1016/j.cancergen.2017.12.002
Abstract: Myeloid neoplasms are a heterogeneous group of hematologic disorders with divergent patterns of cell differentiation and proliferation, as well as divergent clinical courses. Rare recurrent genetic abnormalities related to this group of cancers are associated… read more here.
Keywords: myeloid neoplasms; myeloid neoplasm; molecular approaches; mecom ... See more keywords