Relay Rh(ii)/Pd(0) dual catalysis: synthesis of α-quaternary β-keto-esters via a [1,2]-sigmatropic rearrangement/allylic alkylation cascade of α-diazo tertiary alcohols.
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DOI: 10.1039/c9cc08559a
Abstract: A relay Rh(ii)/Pd(0) dual catalysis that enables domino [1,2]-sigmatropic rearrangement/allylic alkylation of α-diazo tertiary alcohols is described. This transformation represents a highly efficient method for the one-pot synthesis of α-quaternary β-keto-esters under mild conditions, in… read more here.
Keywords: diazo tertiary; relay dual; sigmatropic rearrangement; allylic alkylation ... See more keywords