Dynamic Rearrangement of Cell States Detected by Systematic Screening of Sequential Anticancer Treatments.
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DOI: 10.1016/j.celrep.2017.08.095
Abstract: Signaling networks are nonlinear and complex, involving a large ensemble of dynamic interaction states that fluctuate in space and time. However, therapeutic strategies, such as combination chemotherapy, rarely consider the timing of drug perturbations. If… read more here.
Keywords: dynamic rearrangement; rearrangement cell; drug; cell states ... See more keywords