Stereospecific Overman Rearrangement of Substituted Cyclic Vinyl Bromides: Access to Fully Substituted α-Amino Ketones.
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DOI: 10.1021/acs.orglett.9b03347
Abstract: A versatile thermal Overman rearrangement of enantioenriched, cyclic allylic alcohols providing tertiary allylic amines has been developed. The vinyl bromide used to control enantioselectivity in a preceding CBS reduction is utilized as a synthetic handle… read more here.
Keywords: amino ketones; rearrangement substituted; stereospecific overman; overman rearrangement ... See more keywords
Triplet-sensitised di-π-methane rearrangement of N-substituted 2-azabarrelenones.
Sign Up to like & getrecommendations! Published in 2019 at "Chemical communications"
DOI: 10.1039/c8cc08704k
Abstract: When irradiated at λ = 366 nm or at λ = 420 nm in the presence of an appropriate sensitiser the title compounds underwent a di-π-methane rearrangement which led to the formation of tricyclic azasemibullvalenones… read more here.
Keywords: methane rearrangement; rearrangement substituted; sensitised methane; methane ... See more keywords