Identification of large rearrangements in cancer genomes with barcode linked reads
Sign Up to like & getrecommendations! Published in 2018 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkx1193
Abstract: Abstract Large genomic rearrangements involve inversions, deletions and other structural changes that span Megabase segments of the human genome. This category of genetic aberration is the cause of many hereditary genetic disorders and contributes to… read more here.
Keywords: rearrangements cancer; identification large; cancer; cancer genomes ... See more keywords
Large-Scale Chromatin Rearrangements in Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14102384
Abstract: Simple Summary Cancers have many genetic mutations such as nucleotide changes, deletions, amplifications, and chromosome gains or losses. Some of these genetic alterations directly contribute to the initiation and progression of tumors. In parallel to… read more here.
Keywords: large scale; rearrangements cancer; scale chromatin; chromatin rearrangements ... See more keywords