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Published in 2017 at "Nature Genetics"
DOI: 10.1038/ng.3908
Abstract: A new study shows that aberrant DNA transposase activity promotes structural alterations that are clonally selected to drive tumor development. This discovery uncovers novel mechanisms of tumor-suppressor gene inactivation and highlights a new approach to…
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Keywords:
human tumors;
rearrangements human;
transposase driven;
driven rearrangements ... See more keywords