Conversion of adult endothelium to immunocompetent haematopoietic stem cells
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DOI: 10.1038/nature22326
Abstract: Developmental pathways that orchestrate the fleeting transition of endothelial cells into haematopoietic stem cells remain undefined. Here we demonstrate a tractable approach for fully reprogramming adult mouse endothelial cells to haematopoietic stem cells (rEC-HSCs) through… read more here.
Keywords: adult; rec hscs; endothelial cells; stem cells ... See more keywords