How to communicate and what to disclose to participants in a recall-by-genotype research approach: a multistep empirical study
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Community Genetics"
DOI: 10.1007/s12687-024-00733-8
Abstract: Recall-by-genotype (RbG) is a bottom-up approach using existing genetic data to design follow-up stratified studies. Genetic information may be partially disclosed at invitation, thus raising ethical issues which call for defined best practices for disclosure… read more here.
Keywords: study; approach; recall genotype; research ... See more keywords
Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference
Sign Up to like & getrecommendations! Published in 2018 at "Nature Communications"
DOI: 10.1038/s41467-018-03109-y
Abstract: Detailed phenotyping is required to deepen our understanding of the biological mechanisms behind genetic associations. In addition, the impact of potentially modifiable risk factors on disease requires analytical frameworks that allow causal inference. Here, we… read more here.
Keywords: recall genotype; detailed phenotyping; causal inference; approach ... See more keywords