The RecB helicase-nuclease tether mediates Chi hotspot control of RecBCD enzyme
Sign Up to like & getrecommendations! Published in 2019 at "Nucleic Acids Research"
DOI: 10.1093/nar/gky1132
Abstract: Abstract In bacteria, repair of DNA double-strand breaks uses a highly conserved helicase–nuclease complex to unwind DNA from a broken end and cut it at specific DNA sequences called Chi. In Escherichia coli the RecBCD… read more here.
Keywords: control recbcd; helicase nuclease; nuclease; recbcd enzyme ... See more keywords
RecBCD, SbcCD and ExoI process a substrate created by convergent replisomes to complete DNA replication
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Microbiology"
DOI: 10.1111/mmi.14242
Abstract: The accurate completion of DNA replication on the chromosome requires RecBCD and structure specific SbcCD and ExoI nucleases. However, the substrates and mechanism by which this reaction occurs remains unknown. Here we show that these… read more here.
Keywords: completion; replication; sbccd exoi; recbcd ... See more keywords
Thymine‐starvation‐induced chromosomal fragmentation is not required for thymineless death in Escherichia coli
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DOI: 10.1111/mmi.14897
Abstract: Thymine or thymidine starvation induces robust chromosomal fragmentation in Escherichia coli thyA deoCABD mutants and is proposed to be the cause of thymineless death (TLD). However, fragmentation kinetics challenges the idea that fragmentation causes TLD,… read more here.
Keywords: chromosomal fragmentation; fragmentation; tld; starvation ... See more keywords