Population pharmacokinetics and evaluation of the predictive performance of pharmacokinetic models in critically ill patients receiving continuous infusion meropenem: a comparison of eight pharmacokinetic models
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DOI: 10.1093/jac/dky434
Abstract: Background Several population pharmacokinetic (PopPK) models for meropenem dosing in ICU patients are available. It is not known to what extent these models can predict meropenem concentrations in an independent validation dataset when meropenem is… read more here.
Keywords: receiving continuous; infusion meropenem; pharmacokinetic models; continuous infusion ... See more keywords
Piperacillin Population Pharmacokinetics and Dosing Regimen Optimization in Critically Ill Children Receiving Continuous Renal Replacement Therapy
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DOI: 10.1128/aac.01135-22
Abstract: We aimed to develop a piperacillin population pharmacokinetic (PK) model in critically ill children receiving continuous renal replacement therapy (CRRT) and to optimize dosing regimens. The piperacillin plasma concentration was quantified by high-performance liquid chromatography.… read more here.
Keywords: critically ill; ill children; children receiving; receiving continuous ... See more keywords
Higher Prevalence of Concurrent Thrombocytopenia in Patients Receiving Continuous Renal Replacement Therapy in the Cardiac Intensive Care Unit
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DOI: 10.1159/000513366
Abstract: Introduction: Thrombocytopenia (TCP) is a common finding in patients receiving continuous renal replacement therapy (CRRT). Objective: The purpose of this study was to assess the nature of TCP in patients receiving CRRT. Methods: This is… read more here.
Keywords: continuous renal; receiving continuous; patients receiving; crrt ... See more keywords