Regulation of melanocortin-1 receptor pharmacology by melanocortin receptor accessory protein 2 in orange-spotted grouper (Epinephelus coioides).
Sign Up to like & getrecommendations! Published in 2019 at "General and comparative endocrinology"
DOI: 10.1016/j.ygcen.2019.113291
Abstract: Melanocortin-1 receptor (MC1R) has important roles in regulating pigmentation and inflammation. Melanocortin receptor accessory protein 2 (MRAP2) modulates trafficking, ligand binding, and signaling of mammalian melanocortin receptors. However, the effect of MRAP2 on fish MC1R… read more here.
Keywords: protein; melanocortin receptor; pharmacology; receptor accessory ... See more keywords
Whole-genome sequencing reveals that variants in the Interleukin 18 Receptor Accessory Protein 3'UTR protect against ALS.
Sign Up to like & getrecommendations! Published in 2022 at "Nature neuroscience"
DOI: 10.1038/s41593-022-01040-6
Abstract: The noncoding genome is substantially larger than the protein-coding genome but has been largely unexplored by genetic association studies. Here, we performed region-based rare variant association analysis of >25,000 variants in untranslated regions of 6,139… read more here.
Keywords: receptor accessory; interleukin receptor; protect als; protein ... See more keywords
The roles of interleukin-1 receptor accessory protein in certain inflammatory conditions.
Sign Up to like & getrecommendations! Published in 2022 at "Immunology"
DOI: 10.1111/imm.13462
Abstract: Interleukin-1 receptor accessory protein (IL-1RAcP) is a member of the immunoglobulin superfamily proteins consisting of soluble and membranous isoforms. IL-1RAcP plays an essential role in the signaling of the IL-1 family cytokines such as IL-1,… read more here.
Keywords: receptor accessory; interleukin receptor; accessory protein;
Pharmacological modulation of the cAMP signaling of two isoforms of melanocortin-3 receptor by melanocortin receptor accessory proteins in the tetrapod Xenopus laevis
Sign Up to like & getrecommendations! Published in 2021 at "Endocrine Connections"
DOI: 10.1530/ec-21-0179
Abstract: As a member of the seven-transmembrane rhodopsin-like G protein-coupled receptor superfamily, the melanocortin-3 receptor (MC3R) is vital for the regulation of energy homeostasis and rhythms synchronizing in mammals, and its pharmacological effect could be directly… read more here.
Keywords: receptor accessory; melanocortin receptor; xenopus laevis; receptor ... See more keywords