Comparative analysis of SARS-CoV-2 receptor ACE2 expression in multiple solid tumors and matched non-diseased tissues
Sign Up to like & getrecommendations! Published in 2020 at "Infection, Genetics and Evolution"
DOI: 10.1016/j.meegid.2020.104428
Abstract: Abstract The emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) poses a global public health emergency. SARS-CoV-2 employs the host cell receptor ACE2 for cellular entry. Nonetheless, the differences in ACE2 expression pattern in lung… read more here.
Keywords: ace2 expression; non diseased; receptor ace2; expression ... See more keywords
Human variation in the protein receptor ACE2 affects its binding affinity to SARS-CoV-2 in a variant-dependent manner
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2022.2042387
Abstract: Abstract SARS-CoV-2 infection depend on the binding of the viral Spike glycoprotein (S) to the human receptor Angiotensin Converting Enzyme 2 (ACE2) to induce virus–cell membrane fusion. S protein evolved diverse amino acid changes that… read more here.
Keywords: receptor ace2; binding affinity; sars cov; protein ... See more keywords