Isolation and Purification of Tissue Resident Macrophages for the Analysis of Nuclear Receptor Activity.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9130-3_5
Abstract: Tissue resident macrophages (TRMs) are multifunctional immune cells present in all tissues, contributing to the correct development, homeostasis, and protection against pathogens and injury. TRMs are morphologically and functionally heterogeneous, as a result of both… read more here.
Keywords: tissue resident; tissue; nuclear receptor; receptor activity ... See more keywords
No Effect of Anodal Transcranial Direct Current Stimulation on Gamma-Aminobutyric Acid Levels in Patients with Recurrent Mild Traumatic Brain Injury.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of neurotrauma"
DOI: 10.1089/neu.2016.4399
Abstract: In patients in the chronic phase after recurrent mild traumatic brain injury (mTBI), alterations in gamma-aminobutyric acid (GABA) concentration and receptor activity have been reported, possibly mediating subtle but persistent cognitive deficits and increased rate… read more here.
Keywords: concentration; gaba concentration; stimulation; receptor activity ... See more keywords
Calcineurin Controls Hypothalamic NMDA Receptor Activity and Sympathetic Outflow
Sign Up to like & getrecommendations! Published in 2022 at "Circulation Research"
DOI: 10.1161/circresaha.122.320976
Abstract: Rationale: Hypertension is a common and serious adverse effect of calcineurin inhibitors, including cyclosporine and tacrolimus (FK506). Although increased sympathetic nerve discharges are associated with calcineurin inhibitor–induced hypertension, the sources of excess sympathetic outflow and… read more here.
Keywords: calcineurin; nmda receptor; activity; treatment ... See more keywords
Characterization of an Aplysia vasotocin signaling system and actions of posttranslational modifications and individual residues of the ligand on receptor activity
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2023.1132066
Abstract: The vasopressin/oxytocin signaling system is present in both protostomes and deuterostomes and plays various physiological roles. Although there were reports for both vasopressin-like peptides and receptors in mollusc Lymnaea and Octopus, no precursor or receptors… read more here.
Keywords: aplysia vasotocin; signaling system; activity; receptor activity ... See more keywords
Characterization of Antibodies against Receptor Activity-Modifying Protein 1 (RAMP1): A Cautionary Tale
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232416035
Abstract: Calcitonin gene-related peptide (CGRP) is a key component of migraine pathophysiology, yielding effective migraine therapeutics. CGRP receptors contain a core accessory protein subunit: receptor activity-modifying protein 1 (RAMP1). Understanding of RAMP1 expression is incomplete, partly… read more here.
Keywords: protein ramp1; modifying protein; activity modifying; ramp1 ... See more keywords
Optocontrol of glutamate receptor activity by single side-chain photoisomerization
Sign Up to like & getrecommendations! Published in 2017 at "eLife"
DOI: 10.7554/elife.25808
Abstract: Engineering light-sensitivity into proteins has wide ranging applications in molecular studies and neuroscience. Commonly used tethered photoswitchable ligands, however, require solvent-accessible protein labeling, face structural constrains, and are bulky. Here, we designed a set of… read more here.
Keywords: photoisomerization; glutamate receptor; optocontrol glutamate; receptor ... See more keywords