The soluble receptor for advanced glycation end-products (sRAGE) has a dual phase-dependent association with residual cardiovascular risk after an acute coronary event.
Sign Up to like & getrecommendations! Published in 2019 at "Atherosclerosis"
DOI: 10.1016/j.atherosclerosis.2019.05.020
Abstract: BACKGROUND AND AIMS The pro-inflammatory alarmin S100A12 (EN-RAGE) and the soluble form of its receptor, the receptor for advanced glycation endproducts (sRAGE), have diverging roles in cardiovascular disease. In experimental studies, S100A12 promoted atherosclerosis while… read more here.
Keywords: receptor advanced; cardiovascular risk; risk; srage ... See more keywords
An improved sample extraction method reveals that plasma receptor for advanced glycation end-products (RAGE) modulates circulating free oxytocin in mice
Sign Up to like & getrecommendations! Published in 2021 at "Peptides"
DOI: 10.1016/j.peptides.2021.170649
Abstract: The receptor for advanced glycation end-products (RAGE) binds oxytocin (OT) and transports it from the blood to the brain. As RAGE's OT-binding capacity was lost in RAGE knockout (KO) mice, we predicted that circulating concentrations… read more here.
Keywords: plasma; receptor advanced; method; glycation end ... See more keywords
The receptor for advanced glycation end products: A fuel to pancreatic cancer.
Sign Up to like & getrecommendations! Published in 2018 at "Seminars in cancer biology"
DOI: 10.1016/j.semcancer.2017.07.010
Abstract: The receptor for advanced glycation end products (RAGEs) was first illustrated in the year 1992. RAGE is a single-transmembrane and multi-ligand component of the immunoglobulin protein super family. The engagement of RAGE turns out to… read more here.
Keywords: advanced glycation; receptor advanced; pancreatic cancer; end products ... See more keywords
Affimers as an Alternative to Antibodies in an Affinity LC–MS Assay for Quantification of the Soluble Receptor of Advanced Glycation End-Products (sRAGE) in Human Serum
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Proteome Research"
DOI: 10.1021/acs.jproteome.8b00414
Abstract: Antibodies are indispensable tools in biomedical research, but their size, complexity, and sometimes lack of reproducibility created a need for the development of alternative binders to overcome these limitations. Affimers are a novel class of… read more here.
Keywords: receptor advanced; method; glycation end; advanced glycation ... See more keywords
Chemoenzymatic Synthesis of Heparan Sulfate Mimetic Glycopolymers and Their Interactions with the Receptor for Advanced Glycation End-Product
Sign Up to like & getrecommendations! Published in 2019 at "ACS Macro Letters"
DOI: 10.1021/acsmacrolett.9b00780
Abstract: Heparan sulfate (HS) is a sulfated polysaccharide presenting on the animal cell surface and in the extracellular matrix that plays a critical role in a range of different biological processes. The receptor for advanced glycation… read more here.
Keywords: receptor advanced; mimetic glycopolymers; heparan sulfate; glycation end ... See more keywords
Inhibition of the Receptor for Advanced Glycation End-Products in Acute Respiratory Distress Syndrome: A Randomised Laboratory Trial in Piglets
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-45798-5
Abstract: The receptor for advanced glycation end-products (RAGE) modulates the pathogenesis of acute respiratory distress syndrome (ARDS). RAGE inhibition attenuated lung injury and restored alveolar fluid clearance (AFC) in a mouse model of ARDS. However, clinical… read more here.
Keywords: receptor advanced; acute respiratory; end products; glycation end ... See more keywords
The receptor for advanced glycation end products (RAGE) and DIAPH1: unique mechanisms and healing the wounded vascular system
Sign Up to like & getrecommendations! Published in 2019 at "Expert Review of Proteomics"
DOI: 10.1080/14789450.2018.1536551
Abstract: Diabetes Research Program, Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, New York University School of Medicine, New York, NY, USA; Biomedical Informatics Shared Resource, Herbert Irving Comprehensive Cancer Center, and Department of Biomedical… read more here.
Keywords: medicine; receptor advanced; university; york ... See more keywords
Extracellular matrix glycation and receptor for advanced glycation end-products activation: a missing piece in the puzzle of the association between diabetes and cancer.
Sign Up to like & getrecommendations! Published in 2018 at "Carcinogenesis"
DOI: 10.1093/carcin/bgy012
Abstract: A growing body of epidemiologic evidence suggests that people with diabetes are at a significantly higher risk of many forms of cancer. However, the molecular mechanisms underlying this association are not fully understood. Cancer cells… read more here.
Keywords: receptor advanced; end products; glycation end; cancer ... See more keywords
Beyond the Alveolar Epithelium: Plasma Soluble Receptor for Advanced Glycation End Products Is Associated With Oxygenation Impairment, Mortality, and Extrapulmonary Organ Failure in Children With Acute Respiratory Distress Syndrome.
Sign Up to like & getrecommendations! Published in 2021 at "Critical care medicine"
DOI: 10.1097/ccm.0000000000005373
Abstract: OBJECTIVES Soluble receptor for advanced glycation end products is a known plasma marker of alveolar epithelial injury. However, RAGE is also expressed on cell types beyond the lung, and its activation leads to up-regulation of… read more here.
Keywords: advanced glycation; end products; receptor advanced; glycation end ... See more keywords
Soluble receptor for advanced glycation end products (sRAGE) and asthma: Mendelian randomisation study
Sign Up to like & getrecommendations! Published in 2021 at "Pediatric Allergy and Immunology"
DOI: 10.1111/pai.13478
Abstract: Of the many immune components involved in asthma pathobiology, recent studies have focused on the potential roles of receptor for advanced glycation end products (RAGE).1 RAGE is a member of the immunoglobulin superfamily, which serves… read more here.
Keywords: advanced glycation; receptor advanced; end products; glycation end ... See more keywords
Impact of medium cut‐off membranes on S100A12 and soluble receptor for advanced glycation end products
Sign Up to like & getrecommendations! Published in 2022 at "Seminars in Dialysis"
DOI: 10.1111/sdi.13107
Abstract: Of the most remarkable molecules associated with atherosclerosis and the cardiovascular outcome are S100A12 (10,379.5 Da) and soluble receptor for advanced glycation end products (sRAGE‐42,803 Da) in the hemodialysis (HD) population. We designed a study… read more here.
Keywords: receptor advanced; end products; glycation end; medium cut ... See more keywords