Articles with "receptor allosteric" as a keyword



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In vivo evaluation of the CB1 allosteric modulator LDK1258 reveals CB1-receptor independent behavioral effects

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Published in 2020 at "Pharmacology Biochemistry and Behavior"

DOI: 10.1016/j.pbb.2019.172840

Abstract: In the present study, we examined whether LDK1258, which produces strong CB1 receptor allosteric effects in in vitro assays, would elicit in vivo effects consistent with allosteric activity. In initial studies, LDK1258 reduced food consumption… read more here.

Keywords: cb1 receptor; receptor allosteric; effects vivo; receptor ... See more keywords