Comparison of N-methyl-d-aspartate receptor antibody assays using live or fixed substrates
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DOI: 10.1007/s00415-020-10329-0
Abstract: The diagnostic criteria for N -methyl- d -aspartate receptor antibody (NMDAR-Ab) encephalitis require the presence of CSF antibodies against the NMDAR, whereas serum antibodies are considered specific only if accompanied by CSF antibodies. Current assays… read more here.
Keywords: receptor antibody; methyl aspartate; cba; aspartate receptor ... See more keywords
A Randomized, Double-Blind, Placebo-Controlled Clinical Trial of Tocilizumab, An Interleukin-6 Receptor Antibody, For Residual Symptoms in Schizophrenia
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DOI: 10.1038/npp.2017.258
Abstract: Evidence from preclinical, epidemiological, and human studies indicates that inflammation, and in particular elevated interleukin-6 (IL-6) activity, may be related to clinical manifestations and pathophysiology of schizophrenia. Furthermore, studies in preclinical models suggest that decreasing… read more here.
Keywords: trial; receptor antibody; tocilizumab; placebo ... See more keywords
Anti-interleukin-6 receptor antibody prevents loss of bone structure and bone strength in collagen-induced arthritis mice
Sign Up to like & getrecommendations! Published in 2018 at "Scandinavian Journal of Rheumatology"
DOI: 10.1080/03009742.2017.1416667
Abstract: Objective: Rheumatoid arthritis (RA) is a disease that typically induces secondary osteoporosis, which increases the risk of bone fractures. Anti-interleukin-6 (IL-6) receptor antibody is used to treat RA; however, its effect on bone strength is… read more here.
Keywords: receptor antibody; bone; bone strength; bone structure ... See more keywords
Serum thyroid-stimulating hormone receptor antibody levels and thyroid dysfunction after hysterosalpingography: a case-control study
Sign Up to like & getrecommendations! Published in 2021 at "Gynecological Endocrinology"
DOI: 10.1080/09513590.2021.1963430
Abstract: Abstract Objective Hysterosalpingography (HSG) performed with an iodine contrast media can cause thyroid dysfunction, including thyrotoxicosis and hypothyroidism. We investigated the association between the serum levels of thyroid-stimulating hormone receptor antibody (TRAb), an indicator of… read more here.
Keywords: thyroid stimulating; thyroid dysfunction; hormone receptor; receptor antibody ... See more keywords
Development of type 1 diabetes in a patient treated with anti-interleukin 6 receptor antibody for rheumatoid arthritis.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of diabetes investigation"
DOI: 10.1111/jdi.13706
Abstract: Interleukin-6 (IL-6) is a pleiotropic cytokine that plays pathogenic role in type 1 diabetes (T1D). Therefore, anti-IL-6 receptor antibody, tocilizumab, used for the treatment of rheumatoid arthritis (RA), is considered a candidate for immune intervention… read more here.
Keywords: receptor antibody; type diabetes; receptor; rheumatoid arthritis ... See more keywords
Structural Study of Aavrh.10 Receptor and Antibody Interactions
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DOI: 10.1128/jvi.01249-21
Abstract: Gene therapy vectors based on adeno-associated virus rhesus isolate 10 (AAVrh.10) have been used in several clinical trials to treat monogenetic diseases. However, compared to other AAV serotypes little is known about receptor binding and… read more here.
Keywords: receptor antibody; study; aavrh capsid; receptor ... See more keywords
Coupling of Cortical Hyperintense Signals and Increased Glucose Metabolism in a Case of Anti-GABAA Receptor Antibody-associated Encephalitis.
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DOI: 10.2169/internalmedicine.1535-22
Abstract: We herein report a case of anti-gamma aminobutyric acid type A receptor antibody-associated encephalitis (anti-GABAA-RE) with progressive aphasia and generalized tonic-clonic seizures. Cerebral magnetic resonance imaging (MRI) showed cortical brain lesions coupled with hypermetabolism on… read more here.
Keywords: receptor antibody; encephalitis; anti gabaa;
The Anti-Glucocorticoid Receptor Antibody Clone 5E4: Raising Awareness of Unspecific Antibody Binding
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DOI: 10.3390/ijms23095049
Abstract: Unspecific antibody binding takes a significant toll on researchers in the form of both the economic burden and the disappointed hopes of promising new therapeutic targets. Despite recent initiatives promoting antibody validation, a uniform approach… read more here.
Keywords: unspecific antibody; glucocorticoid receptor; anti glucocorticoid; antibody binding ... See more keywords
Clinical utility of TSH receptor antibody levels in Graves’ orbitopathy: a comparison of two TSH receptor antibody immunoassays
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DOI: 10.5114/ceji.2018.80224
Abstract: Introduction Thyroid stimulating hormone (TSH) receptor antibodies (TRAB) play a role in the development of Graves’ orbitopathy (GO), and measurements of the TRAB level may be helpful in monitoring GO treatment. Aim of the study… read more here.
Keywords: receptor antibody; trab; antibody; tsh receptor ... See more keywords