TNF receptor associated factor 5 controls oncostatin M-mediated lung inflammation.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.03.186
Abstract: Oncostatin M (OSM) is involved in pathogenesis of several human inflammatory diseases including lung inflammation and fibrosis. Although accumulating evidence indicates that OSM mediates lung inflammation, the precise mechanism for OSM on lung inflammation still… read more here.
Keywords: tnf receptor; inflammation; lung inflammation; receptor associated ... See more keywords
Molecular and functional characterization of pigeon (Columba livia) tumor necrosis factor receptor‐associated factor 3
Sign Up to like & getrecommendations! Published in 2017 at "Developmental and Comparative Immunology"
DOI: 10.1016/j.dci.2016.12.005
Abstract: ABSTRACT Tumor necrosis factor receptor‐associated factor 3 (TRAF3) plays a key antiviral role by promoting type I interferon production. We cloned the pigeon TRAF3 gene (PiTRAF3) according to its predicted mRNA sequence to investigate its… read more here.
Keywords: pigeon; tumor necrosis; factor receptor; factor ... See more keywords
Identification and characterization of a TNF receptor-associated factor in Dugesia japonica.
Sign Up to like & getrecommendations! Published in 2019 at "Gene"
DOI: 10.1016/j.gene.2018.09.038
Abstract: The tumor necrosis factor (TNF) superfamily consists of a wide variety of inflammatory cytokine, including cell-bound and secreted proteins. These TNFs function through binding and activation of the TNF receptors for modulating TNF-associated intracellular signals.… read more here.
Keywords: tnf; dugesia japonica; factor; tnf receptor ... See more keywords
Getting a Handle on Neuropharmacology by Targeting Receptor-Associated Proteins
Sign Up to like & getrecommendations! Published in 2017 at "Neuron"
DOI: 10.1016/j.neuron.2017.10.001
Abstract: Targeted therapy for neuropsychiatric disorders requires selective modulation of dysfunctional neuronal pathways. Receptors relevant to CNS disorders typically have associated proteins discretely expressed in specific neuronal pathways; these accessory proteins provide a new dimension for… read more here.
Keywords: associated proteins; handle neuropharmacology; getting handle; neuropharmacology targeting ... See more keywords
H4 Receptor Inhibits Lipopolysaccharide-induced NF-κB Activation by Interacting with Tumor Necrosis Factor Receptor-Associated Factor 6
Sign Up to like & getrecommendations! Published in 2019 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2018.11.050
Abstract: Microglia, the resident immune cells of the central nervous system (CNS), are activated at the beginning of the inflammatory response and induce detrimental neuroinflammation by producing excessive pro-inflammatory cytokines. Nuclear factor kappa B (NF-κB) signaling… read more here.
Keywords: tumor necrosis; receptor; factor receptor; factor ... See more keywords
Pneumococcal Serotype-specific Opsonophagocytic Activity in Interleukin-1 Receptor-associated Kinase 4-deficient Patients.
Sign Up to like & getrecommendations! Published in 2021 at "Pediatric Infectious Disease Journal"
DOI: 10.1097/inf.0000000000003060
Abstract: BACKGROUND The antibody response after pneumococcal vaccines and their effectiveness against invasive pneumococcal disease (IPD) in patients with interleukin-1 receptor-associated kinase 4 (IRAK4) deficiency have not been fully evaluated. Here, we evaluated pneumococcal serotype-specific opsonophagocytic… read more here.
Keywords: interleukin receptor; pneumococcal serotype; associated kinase; deficient patients ... See more keywords
Clinical analysis of Chinese anti‐low‐density‐lipoprotein‐receptor‐associated protein 4 antibodies in patients with myasthenia gravis
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Neurology"
DOI: 10.1111/ene.13979
Abstract: Low‐density‐lipoprotein‐receptor‐associated protein 4 (LRP4) autoantibodies have recently been detected in myasthenia gravis (MG), but little is known about the clinical characteristics associated with this serological type. In this study, the clinical features of Chinese patients… read more here.
Keywords: associated protein; density lipoprotein; low density; myasthenia gravis ... See more keywords
Toxoplasma GRA15 Activates the NF-κB Pathway through Interactions with TNF Receptor-Associated Factors
Sign Up to like & getrecommendations! Published in 2019 at "mBio"
DOI: 10.1128/mbio.00808-19
Abstract: The parasite Toxoplasma can cause birth defects and severe disease in immunosuppressed patients. Strain differences in pathogenicity exist, and these differences are due to polymorphic effector proteins that Toxoplasma secretes into the host cell to… read more here.
Keywords: activation; gra15; receptor associated; factor ... See more keywords
A novel TNFRSF1A mutation associated with TNF-receptor-associated periodic syndrome and its metabolic signature.
Sign Up to like & getrecommendations! Published in 2022 at "Rheumatology"
DOI: 10.1136/annrheumdis-2022-eular.1098
Abstract: OBJECTIVE We describe a family with a novel mutation in the TNF Receptor Superfamily Member 1A gene (TNFRSF1A) causing tumour necrosis factor receptor-associated periodic syndrome (TRAPS) with renal AA-amyloidosis. METHODS Case series of affected family… read more here.
Keywords: tnf receptor; associated periodic; treatment; mutation ... See more keywords
N6-Isopentenyladenosine promoted HeLa cell apoptosis through inhibitions of AKT and transforming growth factor β–activated kinase 1 activation
Sign Up to like & getrecommendations! Published in 2017 at "Tumor Biology"
DOI: 10.1177/1010428317695966
Abstract: N6-Isopentenyladenosine, a member of the family of plant hormones, possesses anti-cancer activities on a number of cancer cell lines. However, its mode of action in cervical cancer cell remains poorly understood. Our computational docking studies… read more here.
Keywords: tumor necrosis; factor receptor; factor; cell ... See more keywords
Multi-locus SNP analyses of interleukin 1 receptor associated kinases 2 gene polymorphisms with the susceptibility to rheumatoid arthritis
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0268496
Abstract: Background The genetic polymorphisms (rs708035, rs3844283) of Interleukin-1 receptor associated kinases 2 (IRAK2) is involved in the NFκB regulatory pathway. The frequencies of IRAK2 gene are unknown in Pakistani population. Therefore, the study was designed… read more here.
Keywords: gene; targeted snps; interleukin receptor; associated kinases ... See more keywords