Impact of prior androgen receptor-axis-targeted agents on the clinical activity of subsequent docetaxel in patients with metastatic castration-resistant prostate cancer: comparative assessment between abiraterone acetate and enzalutamide
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DOI: 10.1007/s12032-017-1060-9
Abstract: The objective of this study was to investigate the impact of prior treatment with androgen receptor-axis-targeted (ARAT) agents, abiraterone acetate (AA) and enzalutamide (Enz), on the activity of subsequently introduced docetaxel in patients with metastatic… read more here.
Keywords: psa; impact; receptor axis; androgen receptor ... See more keywords
The role of the interleukin (IL)-6/IL-6 receptor axis in cancer.
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DOI: 10.1042/bst20180136
Abstract: Interleukin-6 (IL-6) is a pleiotropic cytokine that activates a classic signalling pathway upon binding to its membrane-bound receptor (IL-6R). Alternatively, IL-6 may 'trans-signal' in a manner that is facilitated by its binding to a soluble… read more here.
Keywords: role interleukin; receptor axis; cancer; receptor ... See more keywords
Propensity score‐matched comparison of docetaxel and androgen receptor axis‐targeted agents in patients with castration‐resistant intraductal carcinoma of the prostate
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DOI: 10.1111/bju.14970
Abstract: To evaluate the efficacy of docetaxel and androgen receptor axis‐targeted (ARAT) agents in patients with castration‐resistant prostate cancer (CRPC) with intraductal carcinoma of the prostate (IDC‐P) using a propensity score‐matched analysis. read more here.
Keywords: prostate; docetaxel androgen; receptor axis; axis targeted ... See more keywords