Author response to: Comment on: International multicentre review of perioperative management and outcome for catecholamine‐producing tumours
Sign Up to like & getrecommendations! Published in 2020 at "British Journal of Surgery"
DOI: 10.1002/bjs.11704
Abstract: Editor Yu states that, as in many retrospective studies, our work1 creates the impression that all phaeochromocytomas are more or less the same; an impression that Yu wishes to challenge. We thank Yu for this… read more here.
Keywords: comment; receptor blockade; producing tumours; haemodynamic instability ... See more keywords
Mineralocorticoid receptor blockade with finerenone improves heart function and exercise capacity in ovariectomized mice
Sign Up to like & getrecommendations! Published in 2021 at "ESC Heart Failure"
DOI: 10.1002/ehf2.13219
Abstract: In post‐menopausal women, incidence of heart failure with preserved ejection fraction is higher than in men. Hormonal replacement therapies did not demonstrate benefits. We tested whether the non‐steroidal mineralocorticoid receptor antagonist finerenone limits the progression… read more here.
Keywords: heart; receptor blockade; heart failure; mineralocorticoid receptor ... See more keywords
Neonatal Fc receptor blockade as emerging therapy in diseases with plasma exchange indications.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of clinical apheresis"
DOI: 10.1002/jca.22055
Abstract: Neonatal Fc receptor (FcRn) blockade may represent a mechanism similar to plasma exchange (PLEX) in reducing immunoglobulin levels and thus have a broad implication for apheresis practitioners. Although only efgartigimod received FDA approval for myasthenia… read more here.
Keywords: neonatal receptor; fcrn; receptor blockade; plasma exchange ... See more keywords
Effects of 5-HT5A receptor blockade on amnesia or forgetting
Sign Up to like & getrecommendations! Published in 2019 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2018.01.009
Abstract: &NA; Previously the effects (0.01‐3.0 mg/kg) of post‐training SB‐699551 (a 5‐HT5A receptor antagonist) were reported in the associative learning task of autoshaping, showing that SB‐699551 (0.1 mg/kg) decreased lever‐press conditioned responses (CR) during short‐term (STM;… read more here.
Keywords: receptor blockade; effects ht5a; blockade amnesia; ht5a receptor ... See more keywords
Effects of endothelin receptor blockade and COX inhibition on intestinal I/R injury in a rat model: Experimental research.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of surgery"
DOI: 10.1016/j.ijsu.2020.08.061
Abstract: BACKGROUND Intestinal ischemia is a highly morbid and mortal condition with no specific treatment. The present study aimed to investigate the effects of cyclooxygenase (COX) inhibition synchronized with nitric oxide (NO) release and endothelin (ET)… read more here.
Keywords: receptor blockade; treatment; endothelin receptor; intestinal injury ... See more keywords
IL-6 receptor blockade ameliorates diabetic nephropathy via inhibiting inflammasome in mice.
Sign Up to like & getrecommendations! Published in 2018 at "Metabolism: clinical and experimental"
DOI: 10.1016/j.metabol.2018.01.002
Abstract: BACKGROUND AND OBJECTIVE Interleukin 6 (IL-6) has been identified as a key mediator in inflammation, immune responses and glucose metabolism. In this study, we assessed the effects of an IL-6 receptor antibody on diabetic nephropathy… read more here.
Keywords: receptor blockade; diabetic nephropathy; mice; insulin resistance ... See more keywords
Sex- and Age-dependent Effects of Orexin 1 Receptor Blockade on Open-Field Behavior and Neuronal Activity
Sign Up to like & getrecommendations! Published in 2018 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2018.04.005
Abstract: Adolescence is a sensitive and critical period in brain development where psychiatric disorders such as anxiety, depression and post-traumatic stress disorder are more likely to emerge following a stressful life event. Females are two times… read more here.
Keywords: receptor blockade; field behavior; activity; open field ... See more keywords
Renin–angiotensin system blockade alone or combined with ETA receptor blockade: effects on the course of chronic kidney disease in 5/6 nephrectomized Ren-2 transgenic hypertensive rats
Sign Up to like & getrecommendations! Published in 2017 at "Clinical and Experimental Hypertension"
DOI: 10.1080/10641963.2016.1235184
Abstract: ABSTRACT Background: Early addition of endothelin (ET) type A (ETA) receptor blockade to complex renin–angiotensin system (RAS) blockade has previously been shown to provide better renoprotection against progression of chronic kidney disease (CKD) in Ren-2… read more here.
Keywords: blockade alone; receptor blockade; blockade; receptor ... See more keywords
Endothelin type A receptor blockade attenuates aorto-caval fistula-induced heart failure in rats with angiotensin II-dependent hypertension
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Hypertension"
DOI: 10.1097/hjh.0000000000003307
Abstract: Objective: Evaluation of the effect of endothelin type A (ETA) receptor blockade on the course of volume-overload heart failure in rats with angiotensin II-dependent hypertension. Methods: Ren-2 renin transgenic rats (TGR) were used as a… read more here.
Keywords: receptor; heart failure; receptor blockade; hypertension ... See more keywords
Effects of oxytocin receptor blockade on dyadic social behavior in monogamous and non-monogamous Eulemur
Sign Up to like & getrecommendations! Published in 2022 at "Psychoneuroendocrinology"
DOI: 10.1101/2022.09.14.507945
Abstract: A prominent body of research spanning disciplines has been focused on the potential underlying role for oxytocin in the social signatures of monogamous mating bonds. Behavioral differences between monogamous and non-monogamous vole species, putatively mediated… read more here.
Keywords: non monogamous; behavior monogamous; monogamous non; receptor blockade ... See more keywords
Endothelin‐1 receptor blockade as new possible therapeutic approach in multiple myeloma
Sign Up to like & getrecommendations! Published in 2017 at "British Journal of Haematology"
DOI: 10.1111/bjh.14771
Abstract: New effective treatments are needed to improve outcomes for multiple myeloma (MM) patients. Receptors with restricted expression on plasma cells (PCs) represent attractive new therapeutic targets. The endothelin‐1 (EDN1) axis, consisting of EDN1 acting through… read more here.
Keywords: malignant pcs; receptor blockade; multiple myeloma; endothelin receptor ... See more keywords