Risk of Mild Cognitive Impairment or Probable Dementia in New Users of Angiotensin II Receptor Blockers and Angiotensin-Converting Enzyme Inhibitors
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.20680
Abstract: Key Points Question Is initiation of angiotensin II receptor blockers (ARBs), compared with angiotensin-converting enzyme inhibitors (ACEIs), associated with a reduced risk of cognitive impairment, after controlling for potential pretreatment confounders? Findings This active-comparator, new-user… read more here.
Keywords: new users; angiotensin receptor; cognitive impairment; receptor blockers ... See more keywords
Angiotensin II Receptor Blockers Attenuate Lipopolysaccharide-Induced Memory Impairment by Modulation of NF-κB-Mediated BDNF/CREB Expression and Apoptosis in Spontaneously Hypertensive Rats
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Neurobiology"
DOI: 10.1007/s12035-017-0450-5
Abstract: Clinical studies demonstrated a positive correlation between hypertension and cognitive decline. Beneficial effects of angiotensin II receptor blockers on cognitive functions have also been reported earlier; however, its role in chronic neuroinflammation-induced memory impairment in… read more here.
Keywords: angiotensin receptor; expression; receptor blockers; memory impairment ... See more keywords
Systematic review and meta-analysis of randomised controlled clinical trial evidence refutes relationship between pharmacotherapy with angiotensin-receptor blockers and an increased risk of cancer.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of internal medicine"
DOI: 10.1016/j.ejim.2019.04.019
Abstract: AIMS The potential influence of angiotensin-receptor blockers (ARBs) on carcinogenesis is a much-debated topic. Both observational, as well as preclinical studies in rodent carcinogenic assays, suggest a major role of the Renin-Angiotensin-Aldosterone-System (RAAS) in cancer… read more here.
Keywords: randomised controlled; receptor blockers; angiotensin receptor; cancer ... See more keywords
Angiotensin II receptor blockers suppress the release of stromal cell-derived factor-1α from infarcted myocardium in patients with acute myocardial infarction.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of cardiology"
DOI: 10.1016/j.jjcc.2017.10.002
Abstract: BACKGROUND Although angiotensin II receptor blockers (ARBs) have been shown to have anti-inflammatory effects on infarcted myocardium in experimental models, little is known in humans. Stromal cell-derived factor-1α (SDF-1α), a pro-inflammatory chemokine, is released from… read more here.
Keywords: receptor blockers; months ami; angiotensin receptor; infarcted myocardium ... See more keywords
Potential of angiotensin II receptor blockers in the treatment of diabetic retinopathy
Sign Up to like & getrecommendations! Published in 2017 at "Life Sciences"
DOI: 10.1016/j.lfs.2017.03.020
Abstract: &NA; Impairments in renin‐angiotensin‐aldosterone system during diabetes mellitus, leading to its dysfunction, have been known since a decade. Hyperglycemia induces several pathological alterations which upregulate this system, accounting for overexpression of its downstream signaling molecules,… read more here.
Keywords: receptor blockers; angiotensin receptor; potential angiotensin; diabetic retinopathy ... See more keywords
Associations between brain amyloid accumulation and the use of angiotensin-converting enzyme inhibitors versus angiotensin receptor blockers
Sign Up to like & getrecommendations! Published in 2021 at "Neurobiology of Aging"
DOI: 10.1016/j.neurobiolaging.2020.12.011
Abstract: Some studies suggest that angiotensin II type 1 receptor blockers (ARBs) may protect against memory decline more than angiotensin-converting enzyme inhibitors (ACE-Is), but few have examined possible mechanisms. We assessed longitudinal differences between ARB versus… read more here.
Keywords: accumulation; receptor blockers; use; angiotensin converting ... See more keywords
Angiotensin receptor blockers for the treatment of COVID-19 and its comorbidities
Sign Up to like & getrecommendations! Published in 2020 at "Pharmacological Research"
DOI: 10.1016/j.phrs.2020.104958
Abstract: My recent report (Saavedra, 2020a) warned about the danger of removing ARBs from patients suffering from COVID-19 comorbidities, calling for definitive data analysis to determine whether ARB administration benefited COVID-19 patients. Huang and colleagues disagreed… read more here.
Keywords: covid patients; receptor blockers; covid comorbidities; blockers treatment ... See more keywords
How to deal with the occurrence of rare drug-induced adverse events: the example of sprue-like enteropathy induced by olmesartan medoxomil and other angiotensin-receptor blockers
Sign Up to like & getrecommendations! Published in 2020 at "Blood Pressure"
DOI: 10.1080/08037051.2020.1726101
Abstract: Angiotensin receptor blockers (ARBs) are effective antihypertensive drugs that have been available for the treatment of hypertension, heart failure and nephropathies since the early 1990s. Today, A... read more here.
Keywords: deal occurrence; angiotensin receptor; receptor blockers; occurrence rare ... See more keywords
Angiotensin II receptor blockers in dermatology: a narrative review
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Dermatological Treatment"
DOI: 10.1080/09546634.2022.2089332
Abstract: Abstract Angiotensin II receptor blockers (ARBs) are commonly used for cardiovascular diseases, especially for patients who can’t tolerate the side effects of cough and angioedema caused by angiotensin converting enzyme inhibitors (ACEIs). However, the evidence… read more here.
Keywords: dermatology; narrative review; receptor blockers; angiotensin receptor ... See more keywords
Unspecified intestinal malabsorption in patients treated with angiotensin-converting enzyme inhibitors or angiotensin receptor blockers: a retrospective analysis in primary care settings
Sign Up to like & getrecommendations! Published in 2017 at "Expert Opinion on Drug Safety"
DOI: 10.1080/14740338.2017.1376647
Abstract: ABSTRACT Objective: To investigate the possible relationship between the use of Angiotensin II Receptor Blockers (ARBs) or Angiotensin-Converting-Enzyme Inhibitors (ACE-i) and unspecified intestinal malabsorption (IM) within the Italian and German real-life context. Research design and… read more here.
Keywords: receptor blockers; converting enzyme; angiotensin converting; unspecified intestinal ... See more keywords
Preoperative Administration of Angiotensin-converting Enzyme Inhibitors or Angiotensin II Receptor Blockers: Do We Have Enough "VISION" to Stop It?
Sign Up to like & getrecommendations! Published in 2017 at "Anesthesiology"
DOI: 10.1097/aln.0000000000001405
Abstract: Anesthesiology, V 126 • No 1 1 January 2017 A s of 2012, angiotensinconverting enzyme inhibitors (ACEIs) or angiotensin II receptor blockers (ARBs) were used by approximately 18% of adults in the United states.1 In… read more here.
Keywords: administration; surgery; receptor blockers; angiotensin receptor ... See more keywords