Total Costs of Chimeric Antigen Receptor T-Cell Immunotherapy
Sign Up to like & getrecommendations! Published in 2018 at "JAMA Oncology"
DOI: 10.1001/jamaoncol.2018.0977
Abstract: This study estimates the total costs associated with administering chimeric antigen receptor T-cell treatment. read more here.
Keywords: total costs; antigen receptor; chimeric antigen; receptor cell ... See more keywords
Demographic differences among patients treated with chimeric antigen receptor T‐cell therapy in the United States
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.4797
Abstract: It is not clear if all Americans have benefitted equally from the availability of chimeric antigen receptor T‐cell (CART) therapy. We aimed to evaluate if demographic differences existed among adult patients who received CART therapy… read more here.
Keywords: demographic differences; antigen receptor; receptor cell; chimeric antigen ... See more keywords
Chimeric Antigen Receptor T Cell-Related Neurotoxicity: Mechanisms, Clinical Presentation, and Approach to Treatment
Sign Up to like & getrecommendations! Published in 2019 at "Current Treatment Options in Neurology"
DOI: 10.1007/s11940-019-0580-3
Abstract: Chimeric antigen receptor T cell (CAR-T) adoptive cell therapy is an effective treatment for patients with refractory B cell malignancies. As its use has grown, there has been an increase in the incidence of a… read more here.
Keywords: cell; receptor cell; treatment; neurotoxicity ... See more keywords
Recent updates on chimeric antigen receptor T cell therapy for hepatocellular carcinoma.
Sign Up to like & getrecommendations! Published in 2021 at "Cancer gene therapy"
DOI: 10.1038/s41417-020-00259-4
Abstract: Chimeric antigen receptor T cell (CAR-T) therapy is novel tumor immunotherapy that enables T cells to specifically recognize tumor-associated antigens through genetic engineering technology, thus exerting antitumor effects, and it has achieved encouraging outcomes in… read more here.
Keywords: receptor cell; therapy; antigen receptor; car ... See more keywords
Influence of patient characteristics on chimeric antigen receptor T cell therapy in B-cell acute lymphoblastic leukemia
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-19774-x
Abstract: CD19-specific chimeric antigen receptor T cell (CD19 CAR T) therapy has shown high remission rates in patients with refractory/relapsed B-cell acute lymphoblastic leukemia (r/r B-ALL). However, the long-term outcome and the factors that influence the… read more here.
Keywords: cell acute; cell; receptor cell; therapy ... See more keywords
Potentials, challenges and future of chimeric antigen receptor T-cell therapy in non-Hodgkin lymphomas
Sign Up to like & getrecommendations! Published in 2020 at "Acta Oncologica"
DOI: 10.1080/0284186x.2020.1741680
Abstract: Abstract Background: Diffuse large B-cell lymphoma (DLBCL) is the most common lymphoma subtype. Disease progression or relapse following frontline chemoimmunotherapy, largely in the form of standard R-CHOP, occurs in 30–40% patients. Relapsed/refractory (R/R) DLBCL represents… read more here.
Keywords: therapy; lymphoma; antigen receptor; receptor cell ... See more keywords
Mechanisms of failure of chimeric antigen receptor T-cell therapy
Sign Up to like & getrecommendations! Published in 2019 at "Current Opinion in Hematology"
DOI: 10.1097/moh.0000000000000548
Abstract: Supplemental Digital Content is available in the text read more here.
Keywords: failure chimeric; antigen receptor; receptor cell; mechanisms failure ... See more keywords
Chimeric Antigen Receptor T-Cell Therapy of Neurolymphomatosis Monitored by FDG PET/CT.
Sign Up to like & getrecommendations! Published in 2023 at "Clinical nuclear medicine"
DOI: 10.1097/rlu.0000000000004584
Abstract: ABSTRACT 18F-FDG PET/CT was performed to evaluate possible recurrent B-cell lymphoblastic lymphoma in a 34-year-old man. The images showed multiple foci of increased activity in the nerve root and peripheral nerve. A biopsy confirmed the… read more here.
Keywords: cell; antigen receptor; receptor cell; cell therapy ... See more keywords
Cost‐effectiveness of Anti‐CD19 chimeric antigen receptor T‐Cell therapy in pediatric relapsed/refractory B‐cell acute lymphoblastic leukemia. A societal view
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Haematology"
DOI: 10.1111/ejh.13427
Abstract: In several studies, the chimeric antigen receptor T‐cell therapy tisagenlecleucel demonstrated encouraging rates of remission and lasting survival benefits in pediatric patients with relapsed/refractory (r/r) acute lymphoblastic leukemia (ALL). We assessed the cost‐effectiveness of tisagenlecleucel… read more here.
Keywords: cell; receptor cell; cell therapy; therapy ... See more keywords
Modulation of BCL-2 in both T Cells and Tumor Cells to Enhance Chimeric Antigen Receptor T cell Immunotherapy against Cancer.
Sign Up to like & getrecommendations! Published in 2022 at "Cancer discovery"
DOI: 10.1158/2159-8290.cd-21-1026
Abstract: Chimeric Antigen Receptor T-cell (CART) immunotherapy led to unprecedented responses in patients with refractory/relapsed B-cell non-Hodgkin lymphoma (NHL); nevertheless, two-thirds of patients fail this treatment. Resistance to apoptosis is a key feature of cancer cells… read more here.
Keywords: cell; antigen receptor; receptor cell; chimeric antigen ... See more keywords
Chimeric Antigen Receptor T-Cell Therapy for Lymphomas
Sign Up to like & getrecommendations! Published in 2017 at "Hospital Pharmacy"
DOI: 10.1177/0018578717726517
Abstract: It is estimated that 2.1% of the population of the United States will develop non-Hodgkin lymphoma (NHL) in a lifetime. With treatment, 71% of patients with NHL live to 5 years. Because current drugs used… read more here.
Keywords: car cell; antigen receptor; receptor cell; cell ... See more keywords