Articles with "receptor channel" as a keyword



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The LILI Motif of M3-S2 Linkers Is a Component of the NMDA Receptor Channel Gate

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Published in 2018 at "Frontiers in Molecular Neuroscience"

DOI: 10.3389/fnmol.2018.00113

Abstract: N-methyl-D-aspartate receptors (NMDARs) mediate excitatory synaptic transmission in the central nervous system, underlie the induction of synaptic plasticity, and their malfunction is associated with human diseases. Native NMDARs are tetramers composed of two obligatory GluN1… read more here.

Keywords: glun2b; lili motif; motif linkers; channel ... See more keywords

Molecular Identification of Pro-Excitogenic Receptor and Channel Phenotypes of the Deafferented Lumbar Motoneurons in the Early Phase after SCT in Rats

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms231911133

Abstract: Spasticity impacts the quality of life of patients suffering spinal cord injury and impedes the recovery of locomotion. At the cellular level, spasticity is considered to be primarily caused by the hyperexcitability of spinal α-motoneurons… read more here.

Keywords: excitogenic receptor; identification pro; molecular identification; receptor ... See more keywords