TNF receptor agonists induce distinct receptor clusters to mediate differential agonistic activity
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DOI: 10.1038/s42003-021-02309-5
Abstract: Monoclonal antibodies (mAb) and natural ligands targeting costimulatory tumor necrosis factor receptors (TNFR) exhibit a wide range of agonistic activities and antitumor responses. The mechanisms underlying these differential agonistic activities remain poorly understood. Here, we… read more here.
Keywords: receptor clusters; receptor clustering; differential agonistic; agonistic activity ... See more keywords