Reactivation of Gαi‐coupled formyl peptide receptors is inhibited by Gαq‐selective inhibitors when induced by signals generated by the platelet‐activating factor receptor
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Leukocyte Biology"
DOI: 10.1189/jlb.2a0317-086rr
Abstract: Formyl peptide receptor (FPR)–desensitized neutrophils display increased production/release of superoxide (O2−) when activated by platelet‐activating factor (PAF), a priming of the response achieved through a unique receptor crosstalk mechanism. The aim of this study was… read more here.
Keywords: platelet activating; activating factor; signals generated; receptor crosstalk ... See more keywords
Pleiotropic neurotransmitters: neurotransmitter-receptor crosstalk regulates excitation-inhibition balance in social brain functions and pathologies
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2025.1552145
Abstract: Neuronal excitation-inhibition (E/I) balance is essential for maintaining neuronal stability and proper brain functioning. Disruptions in this balance are implicated in various neurological disorders, including autism spectrum disorder, schizophrenia and epilepsy. The E/I balance is… read more here.
Keywords: receptor crosstalk; crosstalk; inhibition balance; excitation inhibition ... See more keywords