Kupffer cells regulate liver recovery through induction of chemokine receptor CXCR2 on hepatocytes after acetaminophen overdose in mice.
Sign Up to like & getrecommendations! Published in 2021 at "Archives of toxicology"
DOI: 10.1007/s00204-021-03183-0
Abstract: Acetaminophen (APAP) is a widely used analgesic, but also a main cause of acute liver injury in the United States and many western countries. APAP hepatotoxicity is associated with a sterile inflammatory response as shown… read more here.
Keywords: cxcr2; cxcr2 hepatocytes; kupffer cells; chemokine receptor ... See more keywords
The inflammatory chemokine Cxcl18b exerts neutrophil‐specific chemotaxis via the promiscuous chemokine receptor Cxcr2 in zebrafish
Sign Up to like & getrecommendations! Published in 2017 at "Developmental and Comparative Immunology"
DOI: 10.1016/j.dci.2016.10.014
Abstract: ABSTRACT Cxcl18b is a chemokine found in zebrafish and in other piscine and amphibian species. Cxcl18b is a reliable inflammatory marker; however, its function is yet to be elucidated. Here, we found that Cxcl18b is… read more here.
Keywords: chemokine cxcl18b; cxcl18b; chemokine receptor; chemokine ... See more keywords