Novel role for receptor dimerization in post-translational processing and turnover of the GRα
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DOI: 10.1038/s41598-018-32440-z
Abstract: Glucocorticoids (GCs), acting via the glucocorticoid receptor (GRα), remain the mainstay therapeutic choice for the treatment of inflammation. However, chronic GC use, aside from generating undesirable side-effects, results in GRα down-regulation, often coupled to a… read more here.
Keywords: receptor dimerization; dimerization; turnover; post translational ... See more keywords