One amino acid in mouse activated factor VII defines its endothelial protein C receptor (EPCR) binding and modulates its EPCR‐dependent hemostatic activity in vivo
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DOI: 10.1111/jth.13607
Abstract: Essentials The lack of factor (F) VIIa‐endothelial protein C receptor (EPCR) binding in mice is unresolved. A single substitution of Leu4 to Phe in mouse FVIIa (mFVIIa) enables its interaction with EPCR. mFVIIa with a… read more here.
Keywords: epcr binding; protein receptor; receptor epcr; endothelial protein ... See more keywords