Antiepileptic Drug Carbamazepine Binds to a Novel Pocket on the Wnt Receptor Frizzled-8
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DOI: 10.1021/acs.jmedchem.9b02020
Abstract: Misregulation of Wnt signaling is common in human cancer. The development of small molecule inhibitors against the Wnt receptor, frizzled (FZD), may have potential in cancer therapy. During small molecule screens, we observed binding of… read more here.
Keywords: carbamazepine binds; wnt receptor; carbamazepine; receptor frizzled ... See more keywords