Activation of the Zinc-sensing receptor GPR39 promotes T cell reconstitution after hematopoietic cell transplant in mice.
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DOI: 10.1182/blood.2021013950
Abstract: Prolonged lymphopenia represents a major clinical problem after cytoreductive therapies such as chemotherapy and the conditioning required for hematopoietic stem cell transplant (HSCT), contributing toward the risk of infections and malignant relapse. Restoration of T… read more here.
Keywords: gpr39; cell transplant; hsct; receptor gpr39 ... See more keywords
Functions of the Zinc-Sensing Receptor GPR39 in Regulating Intestinal Health in Animals
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DOI: 10.3390/ijms232012133
Abstract: G protein-coupled receptor 39 (GPR39) is a zinc-sensing receptor (ZnR) that can sense changes in extracellular Zn2+, mediate Zn2+ signal transmission, and participate in the regulation of numerous physiological activities in living organisms. For example,… read more here.
Keywords: health; receptor gpr39; intestinal health; zinc sensing ... See more keywords