Heterobivalent Ligand for the Adenosine A2A-Dopamine D2 Receptor Heteromer.
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DOI: 10.1021/acs.jmedchem.1c01763
Abstract: A G protein-coupled receptor heteromer that fulfills the established criteria for its existence in vivo is the complex between adenosine A2A (A2AR) and dopamine D2 (D2R) receptors. Here, we have designed and synthesized heterobivalent ligands… read more here.
Keywords: heteromer; receptor heteromer; adenosine a2a;
Expression of the Adenosine A2A-A3 Receptor Heteromer in Different Brain Regions and Marked Upregulation in the Microglia of the Transgenic APPSw,Ind Alzheimer’s Disease Model
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DOI: 10.3390/biomedicines10020214
Abstract: Adenosine (Ado) receptors have been instrumental in the detection of heteromers and other higher-order receptor structures, mainly via interactions with other cell surface G-protein-coupled receptors. Apart from the first report of the A1 Ado receptor… read more here.
Keywords: appsw ind; alzheimer disease; receptor heteromer; receptor ... See more keywords