Regulation of liver receptor homologue-1 by DDB2 E3 ligase activity is critical for hepatic glucose metabolism
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DOI: 10.1038/s41598-019-41411-x
Abstract: Liver receptor homologue-1 (LRH-1) plays a critical role in hepatic metabolism and disease. Here we show that LRH-1 protein stability is regulated by the cullin 4 (CUL4) E3 ubiquitin ligase complex. We found that DNA… read more here.
Keywords: receptor homologue; metabolism; liver receptor; glucose metabolism ... See more keywords