Risk of Cognitive Effects in Comorbid Patients With Prostate Cancer Treated With Androgen Receptor Inhibitors.
Sign Up to like & getrecommendations! Published in 2021 at "Clinical genitourinary cancer"
DOI: 10.1016/j.clgc.2021.03.014
Abstract: Prostate cancer (PC) is primarily a disease of older men. As the risk of neurocognitive decline increases as people age, cognitive dysfunction is a potential complication in men with PC, imposing detrimental effects on functional… read more here.
Keywords: receptor inhibitors; prostate cancer; cancer; androgen receptor ... See more keywords
Clash of Oral P2Y12 Receptor Inhibitors in Acute Coronary Syndromes.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American College of Cardiology"
DOI: 10.1016/j.jacc.2017.12.004
Abstract: SEE PAGE 371 P 2Y12 receptors on platelet membrane are key modulators of platelet aggregation and thrombosis in acute coronary syndromes (2). Oral P2Y12 receptor inhibitors (clopidogrel, ticagrelor, and prasugrel) combined with aspirin (dual antiplatelet… read more here.
Keywords: receptor inhibitors; oral p2y12; acute coronary; coronary syndromes ... See more keywords
Nicotinic acetylcholine receptor inhibitors derived from snake and snail venoms
Sign Up to like & getrecommendations! Published in 2017 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2017.06.011
Abstract: The nicotinic acetylcholine receptor (nAChR) represents the prototype of ligand-gated ion channels. It is vital for neuromuscular transmission and an important regulator of neurotransmission. A variety of toxic compounds derived from diverse species target this… read more here.
Keywords: receptor inhibitors; nicotinic acetylcholine; receptor; acetylcholine receptor ... See more keywords
Antagonizing P2Y12 Receptor Inhibitors: Current and Future Options.
Sign Up to like & getrecommendations! Published in 2019 at "Thrombosis and haemostasis"
DOI: 10.1055/s-0039-1693738
Abstract: There are clinical scenarios where the balance between the risk of ischemic and bleeding events leads to the clinical decision to reverse the antiplatelet effect of P2Y12 receptor inhibitors. These scenarios comprise emergency situations such… read more here.
Keywords: administration; antagonizing p2y12; receptor inhibitors; effect ... See more keywords
Post-Receptor Inhibitors of the GHR-JAK2-STAT Pathway in the Growth Hormone Signal Transduction
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms19071843
Abstract: The growth hormone (GH) plays a key role in the regulation of metabolic processes in an organism. Determination of the correct structure and functioning of the growth hormone receptor (GHR) allowed for a more detailed… read more here.
Keywords: receptor; growth hormone; post receptor; receptor inhibitors ... See more keywords
Novel Bradykinin Receptor Inhibitors Inhibit Proliferation and Promote the Apoptosis of Hepatocellular Carcinoma Cells by Inhibiting the ERK Pathway
Sign Up to like & getrecommendations! Published in 2021 at "Molecules"
DOI: 10.3390/molecules26133915
Abstract: Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide. Studies have shown that bradykinin (BK) is highly expressed in liver cancer. We designed the novel BK receptor inhibitors J051-71 and J051-105, which reduced the… read more here.
Keywords: hepatocellular carcinoma; apoptosis; receptor inhibitors; cancer ... See more keywords
Clinical outcomes of lenvatinib plus transarterial chemoembolization with or without programmed death receptor-1 inhibitors in unresectable hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2023 at "World Journal of Gastroenterology"
DOI: 10.3748/wjg.v29.i10.1614
Abstract: BACKGROUND Programmed death receptor-1 (PD-1) inhibitors have been approved as second-line treatment regimen in hepatocellular carcinoma (HCC), but it is still worth studying whether patients can benefit from PD-1 inhibitors as first-line drugs combined with… read more here.
Keywords: hepatocellular carcinoma; death receptor; therapy; group ... See more keywords