Articles with "receptor inverse" as a keyword



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Pharmacokinetics and pharmacodynamics of PF‐05190457: The first oral ghrelin receptor inverse agonist to be profiled in healthy subjects

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Published in 2017 at "British Journal of Clinical Pharmacology"

DOI: 10.1111/bcp.13127

Abstract: AIM To evaluate safety, tolerability and pharmacokinetics of oral PF-05190457, an oral ghrelin receptor inverse agonist, in healthy adults. METHODS Single (SAD) and multiple ascending dose (MAD) studies were randomised, placebo-controlled, double-blind studies. Thirty-five healthy… read more here.

Keywords: receptor inverse; ghrelin receptor; inverse agonist; ghrelin ... See more keywords