Control of Glucocorticoid Receptor Levels by PTEN Establishes a Failsafe Mechanism for Tumor Suppression.
Sign Up to like & getrecommendations! Published in 2020 at "Molecular cell"
DOI: 10.1016/j.molcel.2020.09.027
Abstract: The PTEN tumor suppressor controls cell death and survival by regulating functions of various molecular targets. While the role of PTEN lipid-phosphatase activity on PtdIns(3,4,5)P3 and inhibition of PI3K pathway is well characterized, the biological… read more here.
Keywords: phosphatase; receptor levels; phosphatase activity; glucocorticoid receptor ... See more keywords
Characterization of the Glucocorticoid Receptor in Children Undergoing Cardiac Surgery*
Sign Up to like & getrecommendations! Published in 2018 at "Pediatric Critical Care Medicine"
DOI: 10.1097/pcc.0000000000001572
Abstract: Objectives: Postoperative administration of corticosteroids is common practice for managing catecholamine refractory low cardiac output syndrome. Since corticosteroid activity is dependent on the glucocorticoid receptor, we sought to characterize glucocorticoid receptor levels in children undergoing… read more here.
Keywords: surgery; children undergoing; receptor levels; receptor ... See more keywords
Synaptic localization of C9orf72 regulates post-synaptic glutamate receptor 1 levels
Sign Up to like & getrecommendations! Published in 2019 at "Acta Neuropathologica Communications"
DOI: 10.1186/s40478-019-0812-5
Abstract: A hexanucleotide repeat expansion in a noncoding region of C9orf72 is the most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Reduction of select or total C9orf72 transcript and protein levels… read more here.
Keywords: c9orf72; localization; receptor levels; post synaptic ... See more keywords
Vitamin D and vitamin D receptor levels in children with attention-deficit/hyperactivity disorder
Sign Up to like & getrecommendations! Published in 2018 at "Neuropsychiatric Disease and Treatment"
DOI: 10.2147/ndt.s158228
Abstract: Objective In this study, we aimed to evaluate vitamin D and vitamin D receptor levels in children with attention-deficit/hyperactivity disorder (ADHD). Patients and methods In this cross-sectional study, a total of 80 children including 40… read more here.
Keywords: vitamin vitamin; vitamin receptor; receptor levels; levels children ... See more keywords