Design and Synthesis of PEG-Oligoglycerol Sulfates as Multivalent Inhibitors for the Scavenger Receptor LOX-1.
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DOI: 10.1021/acs.biomac.8b01416
Abstract: Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) is a cell surface scavenger receptor. The protein is involved in binding and internalization of oxidized low-density lipoprotein (oxLDL), which leads under pathophysiological circumstances to plaque formation in arteries… read more here.
Keywords: design synthesis; receptor lox; lox; scavenger receptor ... See more keywords