Sigma‐2 receptor and progesterone receptor membrane component 1 (PGRMC1) are two different proteins: Proofs by fluorescent labeling and binding of sigma‐2 receptor ligands to PGRMC1
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DOI: 10.1016/j.phrs.2016.12.023
Abstract: Graphical abstract Figure. No Caption available. Abstract A controversial relationship between sigma‐2 and progesterone receptor membrane component 1 (PGRMC1) proteins, both representing promising targets for the therapy and diagnosis of tumors, exists since 2011, when… read more here.
Keywords: pgrmc1; progesterone receptor; receptor membrane; sigma ... See more keywords
Progesterone receptor membrane associated component 1 enhances obesity progression in mice by facilitating lipid accumulation in adipocytes
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DOI: 10.1038/s42003-020-01202-x
Abstract: Progesterone receptor membrane associated component 1 (PGRMC1) exhibits haem-dependent dimerization on cell membrane and binds to EGF receptor and cytochromes P450 to regulate cancer proliferation and chemoresistance. However, its physiological functions remain unknown. Herein, we… read more here.
Keywords: pgrmc1; progesterone receptor; receptor membrane; receptor ... See more keywords