Activation of the Liver X Receptor Pathway Inhibits HBV Replication in Primary Human Hepatocytes
Sign Up to like & getrecommendations! Published in 2020 at "Hepatology"
DOI: 10.1002/hep.31217
Abstract: Hepatitis B virus (HBV) infection is ranked among the top health priorities worldwide. Accumulating evidence suggests that HBV infection and replication are closely associated with liver metabolism. The liver X receptors (LXRs), which belong to… read more here.
Keywords: liver receptor; receptor pathway; hbv infection; pathway inhibits ... See more keywords
Ulinastatin attenuates neuropathic pain via the ATP/P2Y2 receptor pathway in rat models.
Sign Up to like & getrecommendations! Published in 2017 at "Gene"
DOI: 10.1016/j.gene.2017.06.045
Abstract: Ulinastatin, a serine protease inhibitor, which has anti-inflammatory properties and neuroprotective effects, is used to treat acute inflammatory disorders. Recent evidence indicates that administration of ulinastatin alleviates pain in rat model of neuropathic pain (NPP).… read more here.
Keywords: receptor; atp p2y2; p2y2 receptor; receptor pathway ... See more keywords
Targeting Fibroblast Growth Factor Receptor Pathway: Precision Medicine for Biliary Cancer and Beyond
Sign Up to like & getrecommendations! Published in 2023 at "Seminars in Liver Disease"
DOI: 10.1055/a-2049-3149
Abstract: FGFR2 Inhibitors are now being included in the treatment guidelines of multiple countries for patients with advanced cholangiocarcinoma (CCA). Activation of the FGF-FGFR pathway is related to proliferation and tumor progression. Targeting the FGF-FGFR pathway… read more here.
Keywords: medicine; receptor pathway; factor receptor; targeting fibroblast ... See more keywords
TNF-α-mediated podocyte injury via the apoptotic death receptor pathway in a mouse model of IgA nephropathy
Sign Up to like & getrecommendations! Published in 2022 at "Renal Failure"
DOI: 10.1080/0886022x.2022.2079527
Abstract: Abstract Background IgA nephropathy (IgAN) is the most common primary glomerular disease worldwide and it is characterized by mesangial IgA deposits. Proteinuria is a common clinical feature of IgAN, which has a critical connection to… read more here.
Keywords: death receptor; iga; receptor pathway; podocyte injury ... See more keywords
Genetic variations predicting progression with docetaxel and novel androgen‐receptor pathway inhibitors
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Science"
DOI: 10.1111/cas.15718
Abstract: Genetic variations represented by single‐nucleotide polymorphisms (SNPs) could be helpful for choosing an effective treatment for patients with prostate cancer. This study investigated the prognostic and predictive values of SNPs associated with the prognoses of… read more here.
Keywords: receptor pathway; androgen receptor; progression; pathway inhibitors ... See more keywords
The aryl hydrocarbon receptor pathway plays a central role in the cutaneous response to pollutants
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Dermatology"
DOI: 10.1684/ejd.2022.4262
Abstract: Short- and long-term exposure to atmospheric pollution has significant health effects. The skin is the organ directly in contact with pollutants and is responsible for protection of the organism. Particulate matter (PM) such as polycyclic… read more here.
Keywords: hydrocarbon receptor; pathway plays; aryl hydrocarbon; receptor pathway ... See more keywords
Combination therapy with androgen receptor pathway inhibitors for prostate cancer.
Sign Up to like & getrecommendations! Published in 2023 at "Current cancer drug targets"
DOI: 10.2174/1568009623666230220121610
Abstract: read more here.
Keywords: receptor pathway; androgen receptor; pathway inhibitors; combination therapy ... See more keywords
Proteomic and Transcriptomic Profiling Reveals Mitochondrial Oxidative Phosphorylation as Therapeutic Vulnerability in Androgen Receptor Pathway Active Prostate Tumors
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14071739
Abstract: Simple Summary Metastatic prostate cancer (PC) is the second leading cause of cancer deaths in males. The lack of preclinical models and molecular characterization for advanced stage PC is a key barrier in understanding the… read more here.
Keywords: pathway active; prostate; prostate tumors; cancer ... See more keywords