Role of Peroxisome Proliferator‐Activated Receptor (PPARγ) in Metabolic Disorders in SGA with Catch‐Up Growth
Sign Up to like & getrecommendations! Published in 2018 at "Obesity"
DOI: 10.1002/oby.22030
Abstract: Abnormal fat metabolism is a major disorder in adults who were small for gestational age (SGA). Peroxisome prolferator‐activated receptor (PPARγ) participates in adipocyte differentiation and the regulation of lipid metabolism. This study explored the role… read more here.
Keywords: ppar; receptor ppar; catch growth; activated receptor ... See more keywords
Design, Synthesis, and Evaluation of a Novel Series of Indole Sulfonamide Peroxisome Proliferator Activated Receptor (PPAR) α/γ/δ Triple Activators: Discovery of Lanifibranor, a New Antifibrotic Clinical Candidate.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.7b01285
Abstract: Here, we describe the identification and synthesis of novel indole sulfonamide derivatives that activate the three peroxisome proliferator activated receptor (PPAR) isoforms. Starting with a PPARα activator, compound 4, identified during a high throughput screening… read more here.
Keywords: ppar; peroxisome proliferator; receptor ppar; indole sulfonamide ... See more keywords