Dual conformation of the ligand induces the partial agonistic activity of retinoid X receptor α (RXRα)
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DOI: 10.1002/1873-3468.13301
Abstract: 1‐[(3,5,5,8,8‐pentamethyl‐5,6,7,8‐tetrahydronaphthalen‐2‐yl)amino]benzotriazole‐5‐carboxylic acid (CBt‐PMN), a partial agonist of retinoid X receptor (RXR), has attracted attention due to its potential to treat type 2 diabetes and central nervous system diseases with reduced adverse effects of existing full… read more here.
Keywords: ligand; conformation; receptor rxr; conformation ligand ... See more keywords