Receptor-specific recognition of NPY peptides revealed by structures of NPY receptors
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abm1232
Abstract: In response to three highly conserved neuropeptides, neuropeptide Y (NPY), peptide YY, and pancreatic polypeptide (PP), four G protein–coupled receptors mediate multiple essential physiological processes, such as food intake, vasoconstriction, sedation, and memory retention. Here,… read more here.
Keywords: recognition; recognition npy; specific recognition; npy peptides ... See more keywords
Systems approach reveals distinct and shared signaling networks of the four PGE2 receptors in T cells
Sign Up to like & getrecommendations! Published in 2021 at "Science Signaling"
DOI: 10.1126/scisignal.abc8579
Abstract: Description PGE2 receptors elicit shared, receptor-specific, and cell type–specific downstream signaling in T cells. PGE2 signaling networks The lipid mediator PGE2 suppresses antitumor immunity by activating its four related GPCRs on T cells. Lone et… read more here.
Keywords: pge2 receptors; receptor specific; pge2; signaling networks ... See more keywords