Computational investigation of aphid odorant receptor structure and binding function
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2022.2053743
Abstract: Abstract Odorant receptors (OR) play a critical role in signal transduction and olfactory recognition in insects. Unfortunately, insect ORs are difficult to express and purify, and limited structural data are available. Computational methods were used… read more here.
Keywords: computational investigation; structure; aphid odorant; investigation aphid ... See more keywords
Unveiling the B cell receptor structure
Sign Up to like & getrecommendations! Published in 2022 at "Science"
DOI: 10.1126/science.add8065
Abstract: Description Molecular structures provide a road map for understanding and controlling B cell receptor activation B cells took center stage in the COVID-19 pandemic as the world waited anxiously for a vaccine. Nearly all vaccines… read more here.
Keywords: cell receptor; unveiling cell; cell; receptor structure ... See more keywords
Nanobodies to Study G Protein-Coupled Receptor Structure and Function.
Sign Up to like & getrecommendations! Published in 2017 at "Annual review of pharmacology and toxicology"
DOI: 10.1146/annurev-pharmtox-010716-104710
Abstract: Ligand-induced activation of G protein-coupled receptors (GPCRs) is a key mechanism permitting communication between cells and organs. Enormous progress has recently elucidated the structural and dynamic features of GPCR transmembrane signaling. Nanobodies, the recombinant antigen-binding… read more here.
Keywords: nanobodies study; receptor structure; protein coupled; coupled receptor ... See more keywords
GPR18 receptor – the structure and the role in the physiology and pathophysiology
Sign Up to like & getrecommendations! Published in 2022 at "Postepy biochemii"
DOI: 10.18388/pb.2021_399
Abstract: G-protein coupled receptors constitute the largest family of membrane receptors and they participate in the maintenance of the homeostasis in the body. Some of these receptors still remain orphan receptors as there is insufficient research… read more here.
Keywords: receptor structure; physiology; gpr18 receptor; receptor ... See more keywords
The GABAB Receptor—Structure, Ligand Binding and Drug Development
Sign Up to like & getrecommendations! Published in 2020 at "Molecules"
DOI: 10.3390/molecules25133093
Abstract: The γ-aminobutyric acid (GABA) type B receptor (GABAB-R) belongs to class C of the G-protein coupled receptors (GPCRs). Together with the GABAA receptor, the receptor mediates the neurotransmission of GABA, the main inhibitory neurotransmitter in… read more here.
Keywords: receptor structure; drug; structure ligand; receptor ... See more keywords