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Transferrin receptor 2 (Tfr2) genetic deletion makes transfusion‐independent a murine model of transfusion‐dependent β‐thalassemia

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Published in 2022 at "American Journal of Hematology"

DOI: 10.1002/ajh.26673

Abstract: β‐thalassemia is a genetic disorder caused by mutations in the β‐globin gene, and characterized by anemia, ineffective erythropoiesis and iron overload. Patients affected by the most severe transfusion‐dependent form of the disease (TDT) require lifelong… read more here.

Keywords: transfusion dependent; deletion; iron; transferrin receptor ... See more keywords