Antibody-Drug Conjugates Targeting the Urokinase Receptor (uPAR) as a Possible Treatment of Aggressive Breast Cancer
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DOI: 10.3390/antib8040054
Abstract: A promising molecular target for aggressive cancers is the urokinase receptor (uPAR). A fully human, recombinant antibody that binds uPAR to form a stable complex that blocks uPA-uPAR interactions (2G10) and is internalized primarily through… read more here.
Keywords: drug conjugates; receptor upar; antibody drug; breast cancer ... See more keywords