Involvement of P2X7 receptors in chronic pain disorders.
Sign Up to like & getrecommendations! Published in 2021 at "Purinergic signalling"
DOI: 10.1007/s11302-021-09796-5
Abstract: Chronic pain is caused by cellular damage with an obligatory inflammatory component. In response to noxious stimuli, high levels of ATP leave according to their concentration gradient, the intracellular space through discontinuities generated in the… read more here.
Keywords: pain; p2x7 receptors; involvement p2x7; pain disorders ... See more keywords
Adenosine Metabotropic Receptors in Chronic Pain Management
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.651038
Abstract: The pharmacological treatment of chronic pain is still unsatisfactory. The cellular and molecular mechanisms at the basis of pain chronification are still poorly understood. The commercially available drugs for treating chronic pain, including neuropathic pain,… read more here.
Keywords: neuropathic pain; adenosine; metabotropic; chronic pain ... See more keywords