Vitamin D and Lumisterol Hydroxyderivatives Can Act on Liver X Receptors (LXRs)
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DOI: 10.1210/jendso/bvab048.1671
Abstract: New pathways of vitamin D3 (D3) activation initiated by CYP11A1 and involving other CYPs have been discovered. At least 15 hydroxyderivatives, including 20(OH)D3 as the major product, are generated by these pathways (1,2) with some… read more here.
Keywords: receptor; receptors lxrs; lumisterol; lxr ... See more keywords
Absence of nuclear receptors LXRs impairs immune response to androgen deprivation and leads to prostate neoplasia
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DOI: 10.1371/journal.pbio.3000948
Abstract: Chronic inflammation is now a well-known precursor for cancer development. Infectious prostatitis are the most common causes of prostate inflammation, but emerging evidence points the role of metabolic disorders as a potential source of cancer-related… read more here.
Keywords: absence nuclear; nuclear receptors; receptors lxrs; inflammation ... See more keywords