The role of extracellular vesicles in COVID-19 virus infection
Sign Up to like & getrecommendations! Published in 2020 at "Infection, Genetics and Evolution"
DOI: 10.1016/j.meegid.2020.104422
Abstract: Abstract Extracellular vesicles releasing from various types of cells contribute to intercellular communication via delivering bio-molecules like nucleic acids, proteins, and lipids to recipient cells. Exosomes are 30–120 nm extracellular vesicles that participate in several pathological… read more here.
Keywords: extracellular vesicles; covid virus; recipient cells; infection ... See more keywords
Quantitative Analysis of Extracellular Vesicle Uptake and Fusion with Recipient Cells.
Sign Up to like & getrecommendations! Published in 2022 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.2c00307
Abstract: In precision medicine, extracellular vesicles (EVs) are promising intracellular drug delivery vehicles. The development of a quantitative analysis approach will provide valuable information from the perspective of cell biology and system design for drug delivery.… read more here.
Keywords: recipient; quantitative analysis; recipient cells; uptake fusion ... See more keywords
Mathematical Modeling and Experimental Validation of Extracellular Vesicle-Mediated Tumor Suppressor MicroRNA Delivery and Propagation in Ovarian Cancer Cells.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.2c00525
Abstract: Extracellular vesicle (EV)-mediated microRNA transfer and propagation from the donor cell to the recipient cell in the tumor microenvironment have significant implications, including the development of multidrug resistance (MDR). Although miRNA-encapsulated EV have been shown… read more here.
Keywords: extracellular vesicle; recipient cells; vesicle mediated; model ... See more keywords
Behavior of DNA-lacking mitochondria in Entamoeba histolytica revealed by organelle transplant
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep44273
Abstract: The anaerobic protozoan parasite Entamoeba histolytica has mitosomes that are mitochondria lacking some canonical functions and organelle DNA. Mitosomes play an important role in the life cycle of the parasite. The distribution of proteins in… read more here.
Keywords: lacking mitochondria; behavior dna; dna; recipient cells ... See more keywords
An engineered exosome for delivering sgRNA:Cas9 ribonucleoprotein complex and genome editing in recipient cells.
Sign Up to like & getrecommendations! Published in 2020 at "Biomaterials science"
DOI: 10.1039/d0bm00427h
Abstract: CRISPR-Cas9 is a versatile genome-editing technology that is a promising gene therapy tactic. However, the delivery of CRISPR-Cas9 is still a major obstacle to its broader clinical application. Here, we confirm that the components of… read more here.
Keywords: crispr cas9; cas9; recipient cells; sgrna cas9 ... See more keywords
Suppression of innate immune signaling molecule, MAVS, reduces radiation-induced bystander effect
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Radiation Biology"
DOI: 10.1080/09553002.2020.1807642
Abstract: Abstract Purpose Mitochondrial antiviral signaling (MAVS) protein, located in the mitochondrial out-membrane, is necessary for IFN-beta induction and IFN-stimulated gene expression in response to external stress such as viral invasion and ionizing radiation (IR). Although… read more here.
Keywords: ribe; recipient cells; radiation induced; mavs ... See more keywords
Melatonin promotes the development of sheep transgenic cloned embryos by protecting donor and recipient cells
Sign Up to like & getrecommendations! Published in 2022 at "Cell Cycle"
DOI: 10.1080/15384101.2022.2051122
Abstract: ABSTRACT The yield efficiency of transgenic animal generation is relatively low[1]. To improve its efficiency has become a priority task for researchers[2]. Melatonin (N-acetyl-5-methoxytryptamine, MT) is a potent-free radical scavenger and antioxidant to protect mitochondria,… read more here.
Keywords: donor recipient; development; recipient cells; sheep transgenic ... See more keywords
CD24 Regulates the Formation of Ectosomes in B Lymphocytes
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Extracellular Vesicles"
DOI: 10.1101/2024.08.14.607772
Abstract: CD24 is a glycophosphatidylinositol-linked protein that regulates B cell development. We previously reported that stimulation of CD24 on donor B cells promotes the transfer of functional receptors to recipient B cells via extracellular vesicles (EVs).… read more here.
Keywords: recipient cells; regulates formation; cd24; rock ... See more keywords
Mechanism of recipient cell-dependent differences in exosome uptake
Sign Up to like & getrecommendations! Published in 2017 at "BMC Cancer"
DOI: 10.1186/s12885-017-3958-1
Abstract: BackgroundExosomes, small-membrane vesicles, are secreted by cells and include several types of proteins and nucleic acids. Exosomes transfer cellular information derived from donor cells and are involved in various physiological and pathological events, such as… read more here.
Keywords: mechanism; recipient cells; recipient; exosome uptake ... See more keywords
Shiga Toxin-Bearing Microvesicles Exert a Cytotoxic Effect on Recipient Cells Only When the Cells Express the Toxin Receptor
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2020.00212
Abstract: Shiga toxin is the main virulence factor of non-invasive enterohemorrhagic Escherichia coli strains capable of causing hemolytic uremic syndrome. Our group has previously shown that the toxin can reach the kidney within microvesicles where it… read more here.
Keywords: recipient cells; gb3 positive; toxin; shiga toxin ... See more keywords
Exosomal miR-125b Exerts Anti-Metastatic Properties and Predicts Early Metastasis of Hepatocellular Carcinoma
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.637247
Abstract: Background & Aims Cancer metastasis is responsible for the majority of cancer-related deaths. Exosomal miRNAs have emerged as promising biomarkers for cancer, serving as signaling molecules that can regulate tumor growth and metastasis. This study… read more here.
Keywords: hepatocellular carcinoma; mir 125b; recipient cells; metastasis ... See more keywords